Sodium Taurochenodeoxycholate

Sinónimos: TCDCA sodium salt, Sodium taurochenodeoxycholate, Taurochenodeoxycholic acid sodium salt, 2-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]aminoethanesulfonic acid sodium salt, Chenodeoxycholyltaurine sodium salt

Sodium Taurochenodeoxycholate (TCDCA) is the sodium salt form of taurochenodeoxycholic acid, a primary bile acid conjugated with taurine. It occurs naturally in the bile of mammals, including humans, and plays a critical role in lipid digestion and absorption. As a commercial product, it is typically produced through chemical synthesis or semi-synthesis from chenodeoxycholic acid, ensuring high purity and consistent quality for industrial and research applications.

In the pharmaceutical and biotechnology sectors, TCDCA is valued for its ability to modulate bile acid receptors such as FXR and TGR5, making it a subject of interest in metabolic and liver-related research. It also serves as a key component in cell culture media, particularly for hepatocyte studies, and as a reference standard in analytical chemistry. Its amphiphilic nature allows it to act as a detergent, facilitating the solubilization of membrane proteins and lipids in various biochemical assays.

Product Highlights

• High Purity: ≥98% by HPLC, ensuring reliable performance in sensitive applications.
• Regulatory Support: Manufactured under cGMP conditions; DMF and CEP available upon request.
• Consistent Supply: Annual production capacity exceeding 10 metric tons, with scalable synthesis.
• Quality Assurance: Each batch is tested for assay, residual solvents, heavy metals, and microbial limits.
• Custom Packaging: Available in various pack sizes to meet R&D and production needs.
• Technical Support: Dedicated team to assist with formulation and regulatory inquiries.

Aplicaciones

• Pharmaceutical Research: Used as a tool compound in studies of bile acid signaling, lipid metabolism, and liver diseases.
• Cell Culture: Supplement for hepatocyte maintenance and differentiation media.
• Analytical Standards: Reference material for HPLC, LC-MS, and other analytical methods.
• Biochemical Assays: Employed as a detergent for membrane protein solubilization.
• Nutraceuticals: Investigated for potential health benefits related to bile acid modulation.

Especificaciones

Ordering & Supply

• Embalaje: 1 kg, 5 kg, 25 kg fiber drums with double polyethylene liners.
• MOQ: 1 kg for standard packs; custom quantities available.
• Plazo de entrega: 3-5 días laborables (artículos en stock)
• Documentación: COA, MSDS, TDS, and regulatory support provided with each shipment.
• Storage: Store in a cool, dry place, away from direct sunlight.

Solicitud de presupuesto

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