O-304

O-304

Название продукта O-304
Номер CAS 1261289-04-6
Синонимы O-304, O304, O 304
Молекулярная формула C19H19N3O2S
Молекулярная масса 353.44 g/mol
Внешний вид Кристаллический порошок от белого до небелого цвета
Чистота (ВЭЖХ) ≥98.0%
Растворимость Soluble in DMSO (≥10 mg/mL), slightly soluble in ethanol, practically insoluble in water
Хранение Store at -20°C, protected from light and moisture
Упаковка 10 mg, 50 mg, 100 mg, 500 mg, 1 g in amber glass vials

O-304 Structure

Синонимы: O-304, O304, O 304, 5-[[4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenyl]methyl]-1,3-thiazolidine-2,4-dione

O-304 is a synthetic small-molecule AMPK activator developed for metabolic research. It is manufactured under strict quality control and supplied as a high-purity crystalline powder, typically ≥98% by HPLC. The compound is designed to selectively activate AMPK, a key regulator of cellular energy homeostasis, making it a valuable tool for studying metabolic disorders.

With its favorable pharmacokinetic profile and oral bioavailability demonstrated in preclinical models, O-304 has attracted interest in the research community for its potential in addressing insulin resistance, type 2 diabetes, and related metabolic conditions. It is intended for laboratory and research use only, not for human or veterinary consumption.

Основные особенности продукта

  • Высокая степень чистоты: ≥98% as determined by HPLC, ensuring reliable experimental results.
  • Selective AMPK Activation: Directly activates AMPK without affecting related kinases, providing specificity.
  • Preclinical Validation: Shown to improve insulin sensitivity and glucose uptake in animal models.
  • Scalable Supply: Available in gram to kilogram quantities to support research and early development.
  • Comprehensive Documentation: Each batch comes with a COA, MSDS, and TDS for full traceability.
  • Custom Packaging: Offered in amber vials under inert gas to ensure stability.

Приложения

  • Metabolic disease research, including type 2 diabetes and obesity.
  • Studies on AMPK signaling pathways and energy metabolism.
  • Preclinical drug discovery for insulin sensitizers.
  • Investigation of cellular stress responses and autophagy.
  • Reference standard for analytical method development.

Технические характеристики

Параметр Технические характеристики
Чистота (ВЭЖХ) ≥98.0%
Внешний вид White to off-white powder
Идентификация NMR, MS conform to structure
Потери при сушке ≤0,51 TP3T
Остаток после прокаливания ≤0,11 TP3T
Тяжелые металлы ≤10 ppm
Хранение -20°C, protected from light

Заказы и поставки

  • Packaging: Amber glass vials with PTFE-lined caps, under argon.
  • MOQ: 10 mg; bulk quantities available upon request.
  • Срок выполнения заказа: 3-5 business days for in-stock items; 2-3 weeks for custom synthesis.
  • Documentation: COA, MSDS, TDS provided with each shipment.
  • Доставка: Ambient or refrigerated, depending on destination.

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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