Нуглутил

Синонимы: Nooglutyl, Nooglutil, N-(4-Hydroxyphenylacetyl)-L-prolyl-L-tyrosine, CAS 112193-35-8, Nooglutilum

Nooglutyl is a synthetic dipeptide-like compound that belongs to the nootropic class of agents. It was developed in Russia during the 1990s as part of a research program focused on peptide-based cognitive enhancers. Structurally, it combines a proline residue with a tyrosine moiety and a 4-hydroxyphenylacetyl group, giving it a unique pharmacological profile that distinguishes it from other nootropics.

Nooglutyl is not a natural extract but a fully synthetic molecule. Its chemical structure incorporates a proline ring and a tyrosine-derived phenolic group, which contribute to its ability to cross the blood-brain barrier. This structural design allows it to interact with glutamatergic and GABAergic systems, making it a subject of interest in neurological research.

The compound is typically produced via multi-step organic synthesis, starting from protected amino acids. The final product is purified using recrystallization or chromatography to achieve high purity, usually ≥98% as determined by HPLC. Nooglutyl is primarily used in research settings, particularly in studies investigating cognitive function, neuroprotection, and memory enhancement.

As a research chemical, Nooglutyl is supplied to pharmaceutical companies, academic institutions, and contract research organizations. Its potential applications include the development of treatments for cognitive disorders, neurodegenerative diseases, and age-related memory decline. The compound is also explored as a reference standard in analytical laboratories.

Функция

• Повышение когнитивных способностей: Nooglutyl has been shown to improve memory and learning in animal models, likely through modulation of glutamate receptors.
• Neuroprotective effects: It exhibits protective properties against oxidative stress and excitotoxicity in neuronal cells.
• Anxiolytic activity: The compound displays mild anxiolytic effects in preclinical studies, possibly via GABAergic pathways.
• Antioxidant activity: The phenolic group in its structure contributes to free radical scavenging.
• Modulation of synaptic plasticity: It may influence long-term potentiation, a cellular mechanism underlying memory.

Source & Standardization

• Source: Synthetic, derived from L-proline and L-tyrosine.
• Synthesis: Multi-step peptide coupling and deprotection reactions.
• Standardization: ≥98.0% (HPLC).
• Forms: White to off-white crystalline powder.
• Приложения: Research on cognitive disorders, neuroprotection studies, analytical reference standards.

Технические характеристики

Documentation & Supply

• Monthly capacity: 50 kg
• Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: 1 kg, 5 kg, or 10 kg double-lined aluminum foil bags, or as per customer requirements

Запрос Цитировать

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