Эводиамин

Эводиамин

Product name

Эводиамин

CAS No.

518-17-2

Molecular formula

C19H17N3O

Molecular weight

303.36

Purity

98.0%

Внешний вид

Light yellow crystalline powder

Packing

1kg/ pack

Приложение

Pharmaceutical raw material

What is Evodiamine?

Evodiamine is a bioactive alkaloid extracted from the dried, unripe fruit of Evodia rutaecarpa (also known as Tetradium ruticarpum), a plant used in Traditional Chinese Medicine for centuries. It is the primary active compound responsible for the thermogenic and metabolic effects of the herb.

Evodiamine has become a popular ingredient in weight management and thermogenic formulas due to its ability to increase energy expenditure, reduce appetite, and modulate fat metabolism. It is often positioned as a “non-stimulant thermogenic” alternative to caffeine-based fat burners.

Other name

EVODIAMINE10% PLANTEXTRACT;EVODIAMINE98%;

EVODIAMINE20%PLANTEXTRACT;

EVODIAMINE5%PLANTEXTRACT;

Evodiaminestd ;

EVODIAMINE;

8,13,13b,14-Tetrahydro-14-mChemicalbookethylindolo[2’3′-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one;

Indol(2′,3′:3,4)pyrido(2,1-b)quinazolin-5(7H)-one,8,13,13b,14-tetrahydro-14-methyl-,(S)-

Effect Mechanism
Thermogenesis Activates TRPV1 → increases intracellular calcium → upregulates uncoupling protein 1 (UCP1) in brown adipose tissue
Energy expenditure Increases body temperature and metabolic rate
Appetite suppression Reduces ghrelin (hunger hormone) and food intake (animal studies)
Fat oxidation Enhances lipolysis and fatty acid utilization

Applications

1. Weight Management & Thermogenesis

Приложение Typical Dosage Key Claims
Thermogenic fat burner 50–150 mg/day Increases metabolic rate, calorie burning
Weight management formula 50–100 mg/day Supports healthy weight loss
Non-stimulant fat burner 50–150 mg/day Thermogenesis without jitters

2. Metabolic Health

Приложение Typical Dosage Mechanism
Glucose metabolism support 50–100 mg/day AMPK activation, insulin sensitivity (preclinical)
Lipid profile support 50–100 mg/day May reduce triglycerides, LDL (preclinical)

3. Sports Nutrition

Приложение Typical Dosage Timing
Pre-cardio thermogenic 50–100 mg 30–45 min before cardio
Cutting cycle support 50–150 mg/day Daily during fat loss phase

Evodia rutaecarpa (Juss.)Benth

Поставщик: LyvBio Co., Ltd.

LyvBio Co., Ltd. is a GMP-certified supplier of top purity Evodiamine for the nutraceutical, weight management, and sports nutrition industries.

Возможности поставок:

  • Чистота: ≥98.0% (standard), ≥99.0% (pharmaceutical grade)

  • Source: Evodia rutaecarpa fruit (standardized extract)

  • Ежемесячная производительность: 500+ kg

  • Большие объемы: 100g – 5,000kg

  • Время выполнения: 3-5 дней (образцы), 10-15 дней (опт)

  • Документация: COA, MSDS, HPLC chromatogram, stability data, allergen statement

Specifications

Parameter Standard Grade Test Method
Анализ (ВЭЖХ) ≥ 98.0% HPLC-UV
Внешний вид White to off-white powder Visual
Identification HPLC retention time, IR HPLC/IR
Температура плавления 263–266°C USP <741>
Потери при сушке ≤ 0.5% USP <731>
Residue on Ignition ≤ 0.1% USP <281>
Тяжелые металлы ≤ 10 ppm ICP-MS
Related Substances Single ≤ 0.5%; Total ≤ 2.0% HPLC-UV
Residual Solvents Meet USP <467> GC
Particle Size 95% through 80 mesh Sieve Analysis

 FAQs

Q: Is Evodiamine a stimulant?
A: No. Evodiamine is non-stimulant. It works through TRPV1 activation (calcium signaling), not adrenergic pathways. It does not cause jitters, anxiety, or sleep disruption.

Q: Does Evodiamine cause a burning sensation like capsaicin?
A: No. Despite both activating TRPV1, evodiamine produces thermogenesis (warmth) without the burning/pain sensation of capsaicin. This makes it much more suitable for oral supplements.

Q: How does Evodiamine promote weight loss?
A: Multiple mechanisms: (1) Increases thermogenesis (UCP1 upregulation), (2) Enhances fat oxidation, (3) Reduces appetite (ghrelin suppression – animal data), (4) Inhibits fat cell formation (adipogenesis).

Q: Is Evodiamine safe for long-term use?
A: Human long-term safety data are limited. Typical usage cycles are 8–12 weeks followed by a break. At recommended doses (50–150 mg/day), it is generally well-tolerated.

📧 Электронная почта: info@lyvbio.com
🌐 Веб-сайт: https://www.lyvbio.com

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