Ivermectin

Synonyms: 22,23-Dihydroavermectin B1a, 22,23-Dihydroavermectin B1b, Ivermectin B1a, Ivermectin B1b, MK-933, Ivomec, Stromectol

Ivermectin has become a cornerstone in anti-parasitic portfolios, driven by its broad-spectrum efficacy and well-documented safety profile. As global demand for effective parasiticides continues to rise—particularly in veterinary medicine and public health programs—formulators and procurement teams are increasingly sourcing high-purity Ivermectin to meet production needs.

Ivermectin is a semi-synthetic derivative of avermectin, produced by the soil bacterium Streptomyces avermitilis. It consists of a mixture of two homologous components, B1a and B1b, typically in a ratio of about 80:20. This 16-membered macrocyclic lactone is a potent antiparasitic agent that acts on glutamate-gated chloride channels, leading to paralysis and death of parasites.

Commercially available Ivermectin is standardized to ≥95% purity (sum of B1a and B1b) as determined by HPLC. It is widely used in veterinary and human medicine, and is a key ingredient in formulations targeting nematodes, arthropods, and other parasites. Its stability, efficacy, and established regulatory acceptance make it a preferred choice for pharmaceutical and agrochemical applications.

Product Overview & Composition

Ivermectin is a mixture of two chemically related compounds: 22,23-dihydroavermectin B1a (≥80%) and 22,23-dihydroavermectin B1b (≤20%). The B1a component is the major active ingredient, while B1b contributes to overall efficacy. The product is manufactured through fermentation of S. avermitilis followed by chemical modification.

As a white to off-white crystalline powder, it is practically insoluble in water but freely soluble in organic solvents such as methanol and acetone. This solubility profile allows for versatile formulation approaches, including injectables, pour-ons, and oral drenches in veterinary applications.

Applications & Product Lines

• Veterinary parasiticides: Used in injectable, oral, and topical formulations for cattle, sheep, swine, and companion animals to treat and control internal and external parasites.
• Human medicine: Employed in the treatment of onchocerciasis, strongyloidiasis, and other parasitic infections; also included in mass drug administration programs.
• Agricultural pesticides: Applied to control parasitic insects and mites in crops and livestock environments.
• Research: Utilized in studies on glutamate-gated chloride channels and antiparasitic drug mechanisms.

Quality Control Standards

Bulk Packaging & Supply

• Packaging: 25 kg fiber drum with double polyethylene liner, or as per customer requirements.
• MOQ: 1 kg for trial orders; 25 kg for production quantities.
• Lead time: 3-5 business days for stock items.
• Documentation: COA, MSDS, TDS available upon request.

Frequently Asked Questions

What is the minimum order quantity (MOQ)?

Our MOQ is 1 kg for trial orders and 25 kg for production quantities. We can accommodate larger volumes based on your requirements.

What is the delivery time?

For stock items, delivery time is 3-5 business days from order confirmation.

Do you provide COA and samples?

Yes, we provide a COA for each batch. Samples are available upon request, typically shipped within 1-2 days.

What are the packaging options?

Standard packaging is 25 kg fiber drums with double polyethylene liners. Custom packaging can be arranged to suit your needs.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.