Cytidine

Cytidine

Product Name Cytidine
CAS Number 65-46-3
Molecular Formula C₉H₁₃N₃O₅
Molecular Weight 243.22 g/mol
EINECS Number 200-610-9
Appearance White to off-white crystalline powder
Assay (HPLC) ≥ 99.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Melting Point 210 – 215°C (decomposes)
Specific Rotation +32.0° to +36.0°

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Cytidine is a naturally occurring pyrimidine nucleoside composed of cytosine attached to a ribose sugar via a β-N₁-glycosidic bond. It is a fundamental building block of RNA and plays a critical role in nucleic acid synthesis, cellular metabolism, and membrane biosynthesis. Cytidine is found ubiquitously in all living organisms and is particularly abundant in brain tissue, where it supports neuronal function and synaptic plasticity.

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In addition to its neurological applications, cytidine is used in pharmaceutical formulations, cell culture media, and research applications. Its phosphorylated form, cytidine monophosphate (CMP), and its derivatives, such as cytidine diphosphate choline (CDP-choline, also known as citicoline), are recognized for their neuroprotective and cognitive-enhancing properties.

Related 

Compound Purity CAS No. Key Application Relationship
Cytidine ≥99% 65-46-3 API / Skincare repair Parent compound
Adenosine ≥99% 58-61-7 Anti-aging skincare / API Purine analogue
Guanosine ≥99% 118-00-3 API / Flavor enhancer Purine analogue
Inosine ≥99% 58-63-9 Sports nutrition / API Purine analogue
Uridine ≥99% 58-96-8 Brain health supplements Pyrimidine analogue

Spec

Parameter Specification
Cytidine Content (HPLC) ≥ 99.0%
Identification UV-Vis / IR spectrum conforms to reference
Specific Rotation +32.0° to +36.0°
Melting Point 210 – 215°C (with decomposition)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm
Arsenic (As) ≤ 1 ppm
Microbial Limits Conforms to USP/EP standards

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