Citrulline Malate

Citrulline Malate

Product Name Citrulline Malate
CAS Number 54940-97-5
Molecular Formula C₆H₁₃N₃O₃ · C₄H₆O₅ (ratio dependent)
Molecular Weight ~333.30 g/mol (2:1 ratio)
Appearance White crystalline powder
Assay (HPLC) ≥ 99.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Specific Rotation +21.0° to +25.0°
pH (2% solution) 4.0 – 5.5
Particle Size 100% through 80 mesh
Ratio Options 2:1 (L-Citrulline : DL-Malate) or 1:1 (L-Citrulline : DL-Malate)

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L-Citrulline DL-Malate 2:1 and L-Citrulline DL-Malate 1:1

Synonyms: Citrulline Malate, L-Citrulline DL-Malate, L-Citrulline Malate, Citrulline Malate 2:1, Citrulline Malate 1:1, (S)-2-Amino-5-ureidopentanoic acid malate salt, L-Citrulline α-Hydroxysuccinate

Citrulline Malate is a compound formed by the combination of L-citrulline (a naturally occurring amino acid) and DL-malic acid (an organic acid involved in the Krebs cycle). The combination synergistically supports nitric oxide (NO) production, energy metabolism, and athletic performance. It is available in two molar ratios:

  • 2:1 Citrulline Malate: The most common form for sports nutrition (approx. 67% citrulline / 33% malate).

  • 1:1 Citrulline Malate: Higher malate content (approx. 50% citrulline / 50% malate), suitable for specific formulation requirements.

L-Citrulline is a non-essential amino acid that serves as a precursor to L-arginine and nitric oxide (NO), supporting vasodilation, blood flow, and muscle recovery. Malic acid contributes to ATP production via the Krebs cycle, enhancing energy metabolism and reducing fatigue. The combination has been shown to improve exercise performance, delay fatigue, and support recovery.

Function

  • Nitric oxide precursor: Increases arginine availability, supporting NO‑mediated vasodilation.

  • Blood flow support: Enhances oxygen and nutrient delivery to muscles.

  • Endurance and performance: Reduces fatigue, improves exercise capacity.

  • Recovery support: Decreases muscle soreness and accelerates recovery.

  • Energy metabolism: Malic acid supports ATP production via Krebs cycle.

  • Ammonia detoxification: Citrulline participates in the urea cycle, reducing ammonia accumulation during exercise.

Source & Purity

  • Source: L-Citrulline (fermentation) + DL-Malic acid (chemical synthesis)

  • Standardization: ≥99.0% citrulline malate (HPLC)

  • Ratio Options: 2:1 or 1:1

  • Forms: White crystalline powder

  • Applications: Sports nutrition, dietary supplements, pre‑workout formulations, recovery products

Documentation & Supply

  • Monthly capacity: 5,000+ kg (both ratios)

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

  • Documentation: COA, MSDS

  • Packaging: 1 kg, 5 kg, 10 kg, 25 kg

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