Oxfendazole
| 매개변수 | 사양 |
|---|---|
| 제품명 | Oxfendazole |
| CAS 번호 | 53716-50-0 |
| 분자식 | C15H13N3O3S |
| 분자량 | 315.35 g/mol |
| 외관 | 흰색에서 미백색의 결정성 분말 |
| 분석법 (HPLC) | ≥98.0% |
| 용해도 | Slightly soluble in water, soluble in dimethylformamide, dimethyl sulfoxide |
| 패키지 | 25 kg fiber drum with double polyethylene liner |
도움이 필요하신가요? 저희 팀에 문의해 주세요
동의어: Methyl 5-(phenylsulfinyl)-1H-benzimidazol-2-ylcarbamate, Fenbendazole sulfoxide, Oxfendazole, HOE 8105, Synanthic, 53716-50-0
Oxfendazole is a benzimidazole anthelmintic developed as the sulfoxide metabolite of fenbendazole. It is a white to off-white crystalline powder, practically insoluble in water but soluble in polar aprotic solvents like dimethylformamide and dimethyl sulfoxide. Since its introduction in the 1970s, it has been used extensively in veterinary medicine to control gastrointestinal nematodes, lungworms, and tapeworms in cattle, sheep, and swine. Its efficacy against a broad spectrum of parasites, including benzimidazole-resistant strains, has made it a reliable choice for livestock deworming programs.
Chemically, oxfendazole belongs to the benzimidazole carbamate family. Its structure features a phenylsulfinyl group at the 5-position of the benzimidazole ring, which enhances its anthelmintic activity compared to fenbendazole. The compound acts by binding to β-tubulin, inhibiting microtubule polymerization and disrupting cellular processes in parasites. This mechanism is shared with other benzimidazoles, but oxfendazole’s sulfoxide moiety improves its pharmacokinetic profile, leading to higher plasma concentrations and prolonged efficacy.
In the pharmaceutical industry, oxfendazole is standardized to high purity, typically ≥98% as determined by HPLC. It is primarily used as an active pharmaceutical ingredient (API) in veterinary formulations, including oral suspensions, boluses, and feed premixes. Its broad-spectrum activity and favorable safety profile in target animals make it a key component in parasite control strategies. Additionally, oxfendazole is sometimes employed as a reference standard in analytical laboratories and for research purposes.
| Test Item | 사양 |
|---|---|
| 식별 | IR spectrum conforms to reference standard |
| 건조 손실 | ≤0.5% |
| 소각 잔류물 | ≤0.1% |
| 중금속 | ≤20 ppm |
| Organic Impurities | Total impurities ≤2.0% |
| 잔류 용매 | Meets ICH guidelines |
| Microbial Limits | Total aerobic count ≤1000 CFU/g, yeast and mold ≤100 CFU/g, absence of E. coli and Salmonella |
Our standard MOQ is 25 kg. For smaller quantities, please contact us to discuss your specific requirements.
For stock items, delivery is typically 3-5 business days after order confirmation.
Yes, we provide a COA for each batch. Samples are available upon request for quality evaluation.
send us your specification for a quotation.
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