Acacetin
| 제품명 | Acacetin |
|---|---|
| CAS 번호 | 480-44-4 |
| 다른 이름 | 5,7-Dihydroxy-4'-methoxyflavone; 4'-Methylapigenin; Apigenin 4'-methyl ether |
| 분자식 | C16H12O5 |
| 분자량 | 284.26 g/mol |
| 외관 | Light yellow to yellow crystalline powder |
| 분석법 (HPLC) | ≥98.0% |
| 융점 | 260-265°C |
| 용해도 | Soluble in DMSO, methanol, ethanol; practically insoluble in water |
| 건조 손실 | ≤0.5% |
| 소각 잔류물 | ≤0.1% |
| 중금속 | ≤10 ppm |
| 패키지 | 25 kg fiber drum with double polyethylene liner |
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동의어: 5,7-Dihydroxy-4′-methoxyflavone, 4′-Methylapigenin, Apigenin 4′-methyl ether, Acacetin
Acacetin has been drawing steady attention from formulation scientists and procurement teams alike, largely because it sits at the intersection of two strong trends: the push for multi-target flavonoid actives and the demand for well-characterized, scalable botanical compounds. You’ll find it specified in products ranging from sleep and mood support to metabolic and skin-health formulations, where its flavone backbone offers a distinct profile compared to more common flavonols like quercetin or kaempferol.
Chemically, acacetin is the 4′-methyl ether of apigenin, a flavone aglycone widely distributed in the plant kingdom. It was first isolated from Acacia farnesiana and later identified in a range of species including Chrysanthemum morifolium, Robinia pseudoacacia, and various Lamiaceae herbs. Commercial material is typically obtained either through extraction from botanical sources followed by purification, or by semi-synthetic methylation of apigenin—both routes yielding the same crystalline compound.
Our acacetin is supplied as a high-purity crystalline powder, standardized to ≥98.0% by HPLC, with tight control on residual solvents and heavy metals. It is designed for researchers and formulators who need a reliable, reproducible flavone reference standard or a functional active for advanced development work.
Acacetin belongs to the flavone subclass of flavonoids, characterized by a 2-phenylchromen-4-one skeleton. Its substitution pattern—hydroxyl groups at C5 and C7 and a methoxy group at C4’—gives it a more lipophilic character than apigenin, which often translates into different membrane permeability and metabolic stability in vitro. The compound is a single, well-defined entity, not a mixture, and is routinely characterized by HPLC, NMR, and MS for identity confirmation.
Because it is a pure compound rather than an extract, batch-to-batch consistency is high. The material is typically produced under controlled conditions to minimize oxidation and ensure a stable, free-flowing powder. It is compatible with common organic solvents used in formulation and analytical workflows.
| 매개변수 | 사양 |
|---|---|
| 분석법 (HPLC) | ≥98.0% |
| 건조 손실 | ≤0.5% |
| 소각 잔류물 | ≤0.1% |
| 중금속 | ≤10 ppm |
| Microbial Limits | Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent |
| 잔류 용매 | Conforms to ICH Q3C guidelines |