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What is Evodiamine?

Evodiamine is a bioactive alkaloid extracted from the dried, unripe fruit of Evodia rutaecarpa (also known as Tetradium ruticarpum), a plant used in Traditional Chinese Medicine for centuries. It is the primary active compound responsible for the thermogenic and metabolic effects of the herb.

Evodiamine has become a popular ingredient in weight management and thermogenic formulas due to its ability to increase energy expenditure, reduce appetite, and modulate fat metabolism. It is often positioned as a “non-stimulant thermogenic” alternative to caffeine-based fat burners.

Other name

EVODIAMINE10% PLANTEXTRACT;EVODIAMINE98%;

EVODIAMINE20%PLANTEXTRACT;

EVODIAMINE5%PLANTEXTRACT;

Evodiaminestd ;

EVODIAMINE;

8,13,13b,14-Tetrahydro-14-mChemicalbookethylindolo[2’3′-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one;

Indol(2′,3′:3,4)pyrido(2,1-b)quinazolin-5(7H)-one,8,13,13b,14-tetrahydro-14-methyl-,(S)-

Effect	Mechanism
Thermogenesis	Activates TRPV1 → increases intracellular calcium → upregulates uncoupling protein 1 (UCP1) in brown adipose tissue
Energy expenditure	Increases body temperature and metabolic rate
Appetite suppression	Reduces ghrelin (hunger hormone) and food intake (animal studies)
Fat oxidation	Enhances lipolysis and fatty acid utilization

Applications

1. Weight Management & Thermogenesis

신청	Typical Dosage	Key Claims
Thermogenic fat burner	50–150 mg/day	Increases metabolic rate, calorie burning
Weight management formula	50–100 mg/day	Supports healthy weight loss
Non-stimulant fat burner	50–150 mg/day	Thermogenesis without jitters

2. Metabolic Health

신청	Typical Dosage	Mechanism
Glucose metabolism support	50–100 mg/day	AMPK activation, insulin sensitivity (preclinical)
Lipid profile support	50–100 mg/day	May reduce triglycerides, LDL (preclinical)

3. Sports Nutrition

신청	Typical Dosage	Timing
Pre-cardio thermogenic	50–100 mg	30–45 min before cardio
Cutting cycle support	50–150 mg/day	Daily during fat loss phase

Evodia rutaecarpa (Juss.)Benth

Supplier: LyvBio Co., Ltd.

LyvBio 주식회사. is a GMP-certified supplier of top purity Evodiamine for the nutraceutical, weight management, and sports nutrition industries.

Supply capabilities:

Purity: ≥98.0% (standard), ≥99.0% (pharmaceutical grade)
Source: Evodia rutaecarpa fruit (standardized extract)
Monthly capacity: 500+ kg
Bulk quantities: 100g – 5,000kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, HPLC chromatogram, stability data, allergen statement

Specifications

Parameter	Standard Grade	Test Method
Assay (HPLC)	≥ 98.0%	HPLC-UV
외관	White to off-white powder	Visual
Identification	HPLC retention time, IR	HPLC/IR
Melting Point	263–266°C	USP <741>
건조 손실	≤ 0.5%	USP <731>
Residue on Ignition	≤ 0.1%	USP <281>
중금속	10 ppm 이하	ICP-MS
Related Substances	Single ≤ 0.5%; Total ≤ 2.0%	HPLC-UV
Residual Solvents	Meet USP <467>	GC
Particle Size	95% through 80 mesh	Sieve Analysis

FAQs

Q: Is Evodiamine a stimulant?
A: No. Evodiamine is non-stimulant. It works through TRPV1 activation (calcium signaling), not adrenergic pathways. It does not cause jitters, anxiety, or sleep disruption.

Q: Does Evodiamine cause a burning sensation like capsaicin?
A: No. Despite both activating TRPV1, evodiamine produces thermogenesis (warmth) without the burning/pain sensation of capsaicin. This makes it much more suitable for oral supplements.

Q: How does Evodiamine promote weight loss?
A: Multiple mechanisms: (1) Increases thermogenesis (UCP1 upregulation), (2) Enhances fat oxidation, (3) Reduces appetite (ghrelin suppression – animal data), (4) Inhibits fat cell formation (adipogenesis).

Q: Is Evodiamine safe for long-term use?
A: Human long-term safety data are limited. Typical usage cycles are 8–12 weeks followed by a break. At recommended doses (50–150 mg/day), it is generally well-tolerated.

📧 Email: info@lyvbio.com
🌐 Website: https://www.lyvbio.com

태그:

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Product name	에보디아민
CAS No.	518-17-2
Molecular formula	C19H17N3O
Molecular weight	303.36
Purity	98.0%
외관	Light yellow crystalline powder
Packing	1kg/ pack
신청	Pharmaceutical raw material

에보디아민