Afoxolaner

Afoxolaner (CAS 1093861-60-9) is a systemic isoxazoline ectoparasiticide developed for veterinary use, primarily in dogs. It acts by inhibiting GABA- and glutamate-gated chloride channels, leading to rapid paralysis and death of fleas and ticks. This compound is supplied as a white to off-white crystalline powder with ≥98% HPLC purity, suitable for oral solid dosage forms.

동의어: 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-(2,2,2-trifluoroethyl)amino]ethyl]-, (5S)-; Afoxolaner (USAN); NexGard® active ingredient; 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide

응용 분야

• Veterinary formulations for flea and tick control in dogs
• Combination products with other parasiticides (e.g., milbemycin oxime)
• R&D and scale-up for oral tablet development

품질 및 문서화

Every batch is tested for assay (HPLC ≥98%), loss on drying (≤0.5%), and heavy metals (≤10 ppm). Full COA, MSDS, and TDS are provided per batch. Stability data and impurity profiles are available on request for qualification.

포장 및 공급

표준 포장: 1kg, 5kg, 25kg. 맞춤형 포장 및 대량 공급도 가능합니다. 재고가 있는 상품은 3~5일 이내에 발송됩니다. 최소 주문 수량(MOQ)은 1kg부터입니다. 가격, 샘플 또는 대량 주문에 대해서는 영업팀에 문의해 주십시오.

견적 요청

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