Citrulline Malate

Citrulline Malate

製品名 Citrulline Malate
CAS番号 54940-97-5
同義語 L-Citrulline DL-Malate, Citrulline Malate 2:1, L-Citrulline malate
分子式 C10H19N3O8
分子量 309.27 g/mol
外観 白色からオフホワイトの結晶性粉末
アッセイ ≥98.0%(HPLC)
乾燥減量 ≤0.5%
重金属 10 ppm以下
溶解度 Soluble in water
パッケージ 25 kg fiber drum with double PE liner

Citrulline Malate Structure

同義語: L-Citrulline DL-Malate, Citrulline Malate 2:1, L-Citrulline malate

Citrulline Malate has become a go-to ingredient for formulators targeting nitric oxide support and athletic endurance. Its popularity stems from a simple fact: it delivers more usable L-citrulline to the bloodstream than L-citrulline alone, thanks to the malate component that feeds the Krebs cycle. Sports nutrition brands, pre-workout manufacturers, and clinical nutrition companies have all adopted it as a core active.

Chemically, it is a 1:1 salt of L-citrulline and DL-malic acid, though commercial grades often use a 2:1 ratio (two citrulline to one malate) to maximize the citrulline payload. L-Citrulline itself is a non-protein amino acid first isolated from watermelon, while malic acid is a dicarboxylic acid found in apples and other fruits. The combination is not just additive—malate replenishes tricarboxylic acid cycle intermediates, which can enhance energy production during exercise.

LyvBio supplies Citrulline Malate in a highly purified, crystalline form standardized to ≥98% assay by HPLC. Our material is manufactured via enzymatic conversion and salt formation, followed by crystallization and drying. It is non-GMO, allergen-free, and suitable for vegan and vegetarian formulations.

製品の概要と成分

Citrulline Malate consists of L-citrulline and DL-malic acid in a defined molar ratio. The most common commercial form is 2:1 (L-citrulline:DL-malic acid), which provides approximately 65% L-citrulline by weight. This ratio is favored because it allows for higher citrulline dosing without exceeding label claims or causing gastrointestinal discomfort.

The malate portion is not a filler—it plays an active role in cellular energy metabolism. Malate is a key intermediate in the malate-aspartate shuttle and the Krebs cycle, helping to sustain ATP production under anaerobic conditions. Together, the two components work synergistically to support nitric oxide synthesis, ammonia clearance, and muscular endurance.

主な用途

  • スポーツ栄養学: Pre-workout powders, intra-workout drinks, and recovery formulas for endurance and strength athletes.
  • Clinical nutrition: Used in medical foods for conditions involving impaired ammonia detoxification or muscle wasting.
  • Functional beverages: Ready-to-drink energy and hydration products seeking a non-stimulant performance boost.
  • Dietary supplements: Capsules and tablets targeting vascular health and exercise performance.
  • 研究: Studied for its effects on nitric oxide bioavailability, exercise capacity, and protein metabolism.

品質と基準

パラメータ 仕様
分析(HPLC) ≥98.0%
外観 白色からオフホワイトの結晶性粉末
乾燥減量 ≤0.5%
重金属 10 ppm以下
総細菌数 1000 CFU/g以下
酵母・カビ 100 CFU/g以下
E. coli / Salmonella Negative

包装・供給

  • パッケージ: 25 kg fiber drums with double polyethylene liners, or customized packaging upon request.
  • 最小注文数量(MOQ): 25 kg (1 drum).
  • リードタイム: 3~5営業日(在庫品)
  • ドキュメント: COA, MSDS, TDS, and nutritional statements available.

見積依頼

  • リブバイオ株式会社. — メールアドレス: info@lyvbio.com

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