| Product Name | Kojic Acid Dipalmitate |
| CAS Number | 79725-98-7 |
| Molecular Formula | C₃₈H₆₆O₆ |
| Molecular Weight | 618.93 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | 92–96°C |
| Acid Value | ≤ 5.0 mg KOH/g |
| Storage | Cool, dry, sealed, protected from light |
| Shelf Life | 36 months |
| Package | 100g, 500g, 1kg, 5kg, 25kg |
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Kojic Acid Dipalmitate is a lipid-soluble derivative of kojic acid, created by esterifying kojic acid with palmitic acid. This structural modification addresses the two major limitations of free kojic acid: poor stability (oxidation, discoloration) and poor skin penetration (hydrophilic) .
Key differentiator: Kojic Acid Dipalmitate is the most stable and skin-bioavailable form of kojic acid, delivering superior brightening efficacy with no formulation discoloration (unlike free kojic acid which turns yellow/brown over time).
Why the market has shifted:
| Parameter | Kojic Acid | Kojic Acid Dipalmitate |
|---|---|---|
| Solubility | Water-soluble | Oil-soluble |
| Stability (color) | Unstable (oxidizes yellow→brown) | Stable (no discoloration) |
| Stability (heat) | Degrades >50°C | Stable >80°C |
| Skin penetration | Poor (hydrophilic) | Excellent (lipophilic) |
| Tyrosinase inhibition | Potent (direct) | Potent (after enzymatic hydrolysis) |
| Sustained release | No (rapid) | Yes (gradual release of active kojic acid) |
| Formulation pH | Narrow (4–6) | Broad (4–8) |
| Shelf life | 12–18 months | 36 months |
| Discoloration risk | High (browning) | None |
| Irritation potential | Moderate (high dose) | Low (gradual release) |
| Application | Typical Usage | Key Claims |
|---|---|---|
| Melasma treatment creams | 1–2% | Reduces dark patches, even skin tone |
| Dark spot correctors | 1–2% | Fades age spots, sun spots, post-acne marks |
| Brightening serums | 0.5–1.5% | Illuminates, evens complexion |
| All-over body lotions | 0.5–1% | Even skin tone on arms, legs, décolletage |
| Application | Typical Usage | Positioning |
|---|---|---|
| Luminous anti-aging creams | 0.5–1.5% | Brightening + wrinkle reduction |
| Night renewal treatments | 1–2% | Overnight brightening + cell turnover |
| Vitamin C combination serums | 0.5–1% | Multi-pathway brightening + antioxidant |
| Application | Typical Usage | Target Consumer |
|---|---|---|
| Post-acne spot treatment | 1–2% | Acne-prone skin with residual marks |
| Post-procedure brightening | 0.5–1% | After laser, chemical peel (clinical use) |
| Pregnancy-safe brightening | 0.5–1% | Melasma / dark spots (safe alternative to hydroquinone) |
LyvBio Co., Ltd. is supplier of high-purity Kojic Acid Dipalmitate for the cosmetic and personal care industry.
Supply capabilities:
Purity: ≥98.0% (HPLC)
Monthly capacity: 500+ kg
Bulk quantities: 100g – 5,000kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, TDS, HPLC chromatogram, stability data
Packaging: 100g, 500g, 1kg, 5kg, 25kg (foil bag or HDPE drum)
| Parameter | Kojic Acid Dipalmitate | Kojic Acid | Hydroquinone | Alpha-Arbutin | Tranexamic Acid |
|---|---|---|---|---|---|
| Solubility | Oil | Water | Water | Water | Water |
| Stability | Excellent | Poor | Good | Good | Excellent |
| Discoloration risk | None | High | Low | None | None |
| Skin penetration | High | Low | High | Moderate | Low-Moderate |
| Tyrosinase inhibition | Potent (after hydrolysis) | Potent | Potent | Moderate | None (different pathway) |
| Melasma efficacy | High | Moderate | Very High | Moderate | High |
| Cytotoxicity | None | Low | Yes (at high conc.) | None | None |
| Regulatory (EU/US) | Allowed | Allowed | Restricted (US), Banned (EU) | Allowed | Allowed |
| Clean beauty | Good | Moderate | Poor | Good | Good |
| Pregnancy safe | Yes | Yes | No | Yes | Yes |
Q: What is the difference between Kojic Acid and Kojic Acid Dipalmitate?
A: Kojic Acid Dipalmitate is the oil-soluble, stabilized ester of kojic acid. It is more stable (no discoloration), better penetrating, and easier to formulate than free kojic acid. It hydrolyzes on skin to release active kojic acid.
Q: Is Kojic Acid Dipalmitate more effective than Kojic Acid?
A: Yes, in finished formulations. Although free kojic acid has higher in vitro tyrosinase inhibition, its poor stability and penetration limit real-world efficacy. Kojic Acid Dipalmitate delivers more active kojic acid to melanocytes due to better penetration and stability.
Q: Does Kojic Acid Dipalmitate cause skin irritation?
A: No. It is non-irritating at recommended concentrations (0.5–2.0%). The gradual release of kojic acid reduces irritation potential compared to free kojic acid.
Q: Can Kojic Acid Dipalmitate be used during pregnancy?
A: Yes. Unlike hydroquinone, kojic acid derivatives have no known teratogenic risk. However, consult a physician before use.
Q: How should Kojic Acid Dipalmitate be stored?
A: Cool, dry, sealed, protected from light. Shelf life: 36 months.
Q: Is Kojic Acid Dipalmitate soluble in water?
A: No. It is oil-soluble. For water-based serums, use solubilizers or emulsify.
Q: What is your MOQ?
A: Sample orders: 100g–500g. Trial production: 1–5 kg. Commercial: Negotiable (25kg+ receives volume pricing). Lead time: 3–5 days (samples); 10–15 days (bulk).
📧 Email: info@lyvbio.com
🌐 Website: https://www.lyvbio.com
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