Guanosine

Guanosine

Nom du produit Guanosine
Numéro CAS 118-00-3
Synonymes Guanine riboside; 9-β-D-Ribofuranosylguanine; Guanine-9-β-D-ribofuranoside; Vernine; 2-Amino-9-β-D-ribofuranosyl-9H-purine-6(1H)-one
Formule moléculaire C10H13N5O5
Poids moléculaire 283.24 g/mol
Apparence Poudre cristalline blanche à blanc cassé
Essai (HPLC) ≥98,01 TP3T
Point de fusion 250 °C (dec.)
Solubilité Sparingly soluble in water (0.75 g/L at 25 °C); practically insoluble in ethanol, acetone
Perte au séchage ≤ 0,51 TP3T
Résidu au feu ≤ 0,11 TP3T
Métaux lourds ≤ 10 ppm
Stockage Store in a cool, dry place, protected from light and moisture

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Guanosine Structure

Synonymes : Guanine riboside, 9-β-D-Ribofuranosylguanine, Guanine-9-β-D-ribofuranoside, Vernine, 2-Amino-9-β-D-ribofuranosyl-9H-purine-6(1H)-one

Guanosine is a purine nucleoside composed of a guanine base linked to a ribose sugar via a β-N9-glycosidic bond. It occurs naturally in RNA and is produced industrially through fermentation or chemical synthesis, typically offered at ≥98% purity for pharmaceutical and biotech applications.

As a key intermediate in nucleotide metabolism, guanosine serves as a precursor to guanylic acid (GMP) and its derivatives, which are widely used as flavor enhancers and pharmaceutical actives. Its role in cellular signaling and energy transfer makes it a valuable building block for antiviral, anticancer, and cardiovascular research, as well as a standard in analytical laboratories.

Product Highlights

  • High purity: ≥98% by HPLC, suitable for sensitive applications including cell culture and molecular biology.
  • Reliable supply: Produced via fermentation with consistent quality, available in ton-scale quantities.
  • Regulatory support: Full documentation including COA, MSDS, and TDS for seamless regulatory submissions.
  • Custom packaging: Offered in quantities from grams to kilograms, with custom packaging options to meet specific handling needs.
  • Fast turnaround: Stocked in multiple warehouses for rapid global delivery.
  • Technical expertise: Backed by a team experienced in nucleoside chemistry and application development.

Applications

  • Pharmaceutical intermediates for antiviral and anticancer drugs (e.g., acyclovir, ganciclovir analogs).
  • Nutritional supplements and functional foods, often in combination with other nucleotides.
  • Biochemical research: substrate for GTP-dependent enzymes, signal transduction studies.
  • Flavor enhancement: precursor to guanosine monophosphate (GMP), a umami tastant.
  • Diagnostic reagents and analytical standards.

Caractéristiques techniques

Paramètre Spécifications
Essai (HPLC) ≥98,01 TP3T
Apparence Poudre cristalline blanche à blanc cassé
Identification IR spectrum conforms to reference
Perte au séchage ≤ 0,51 TP3T
Résidu au feu ≤ 0,11 TP3T
Métaux lourds ≤ 10 ppm
Solubilité Sparingly soluble in water

Ordering & Supply

  • Conditionnement : 1 kg, 5 kg, 25 kg fiber drums with double polyethylene liners; custom packaging available.
  • MOQ: 1 kg (sample orders negotiable).
  • Délai de livraison: 3 à 5 jours ouvrés (articles en stock)
  • Documentation : COA, MSDS, TDS provided with each shipment; additional regulatory support available upon request.
  • Storage: Store in a cool, dry place, protected from light and moisture.

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