Kaempferol

Kaempferol

Produktname Kaempferol
Synonyme 3,4',5,7-Tetrahydroxyflavone;

Robigenin;

Pelargidenolon;

Kaempferide

CAS-Nummer 520-18-3
Molekülformel C₁₅H₁₀O₆
Molekulargewicht 286.24 g/mol
EINECS-Nummer 208-287-6
Aussehen Yellow to greenish-yellow crystalline powder
Analyse (HPLC) ≥ 98,01 TP3T
Trocknungsverlust ≤ 1,01 TP3T

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Kaempferol is a naturally occurring flavonol belonging to the flavonoid class of polyphenolic compounds.

It is widely distributed in the plant kingdom, found in a variety of dietary sources including tea, broccoli, cabbage, kale, beans, endive, leek, tomato, strawberries, and grapes.

It is also present in medicinal plants such as Ginkgo biloba und Sophora japonica.

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Kaempferol has been extensively studied for its potential in cardiovascular protection, neuroprotection, metabolic health, and cancer chemoprevention.

Its mechanisms include activation of Nrf2, inhibition of NF-κB, and modulation of PI3K/Akt and MAPK pathways.

As one of the most abundant dietary flavonoids, kaempferol is recognized as a promising bioactive compound for health promotion and disease prevention.

Funktion

  • Potent antioxidant: Directly scavenges ROS and chelates transition metals.

  • Unterstützung des Herz-Kreislauf-Systems: Improves endothelial function, reduces oxidative stress in vascular tissues.

  • Neuroprotective activity: Protects neurons from oxidative damage and supports cognitive function.

  • Metabolic regulation: Modulates glucose and lipid metabolism via AMPK activation.

 Reinheit

  • Standardisierung: ≥98.0% kaempferol (HPLC)

  • Formulare: Crystalline powder (aglycone)

  • Anwendungen: Dietary supplements, pharmaceutical research, analytical standards, cosmetic formulations

Related Compounds

Verbundstoff CAS-Nr. Key Application Beziehung
Kaempferol 520-18-3 Antioxidant, cardiovascular, neuroprotection Parent compound
Quercetin 117-39-5 Antioxidant, immune support, cardiovascular Flavonol analogue (one more OH group)
Myricetin 529-44-2 Antioxidant, metabolic health Flavonol analogue (three OH groups)
Kaempferol-3-O-glucoside (Astragalin) 480-10-4 Antioxidativ, entzündungshemmend Glycosylated derivative
Rutin 153-18-4 Antioxidant, vascular support Flavonol glycoside

Spec

Parameter Technische Daten
Kaempferol Content (HPLC) ≥ 98,01 TP3T
Identifizierung Das UV-Vis-/IR-Spektrum stimmt mit der Referenz überein
Schmelzpunkt 276 – 278°C
Trocknungsverlust ≤ 1,01 TP3T
Verbrennungsrückstand ≤ 0,5%
Schwermetalle (als Pb) ≤ 10 ppm
Arsen (As) ≤ 1 ppm

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