| Produktname | Metformin Hydrochloride |
|---|---|
| CAS-Nummer | 1115-70-4 |
| Molekülformel | C₄H₁₁N₅ · HCl |
| Molekulargewicht | 165.62 g/mol |
| Aussehen | Weißes, kristallines Pulver |
| Analyse (HPLC) | ≥ 98,01 TP3T |
| Trocknungsverlust | ≤ 0,5% |
| Verbrennungsrückstand | ≤ 0,11 TP3T |
| Schwermetalle | ≤ 10 ppm |
| Schmelzpunkt | 223 – 226°C |
| pH-Wert (1%-Lösung) | 5.0 – 7.0 |
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Metformin Hydrochloride is a biguanide compound and the hydrochloride salt form of metformin. It is one of the most widely prescribed oral antidiabetic agents in the world, recognized as the first‑line pharmacological treatment for type 2 diabetes mellitus. Metformin has been used clinically for over 60 years and is included on the WHO Model List of Essential Medicines.
Metformin works primarily by reducing hepatic glucose production (gluconeogenesis), increasing peripheral insulin sensitivity, and enhancing glucose uptake in muscle and adipose tissue. It also has beneficial effects on lipid metabolism and body weight, making it a preferred choice for patients with type 2 diabetes and obesity.
In addition to its antidiabetic applications, metformin is widely studied for its potential in anti‑aging, cardiovascular health, polycystic ovary syndrome (PCOS), and cancer prevention. Its safety profile, low cost, and multifactorial benefits have made it a compound of significant research interest beyond diabetes management.
Hepatic glucose reduction: Inhibits gluconeogenesis and glycogenolysis in the liver.
Insulin sensitivity improvement: Enhances peripheral glucose uptake and utilization.
Weight management: Associated with weight neutrality or modest weight loss.
Unterstützung bei der Regulierung des Fettstoffwechsels: Modulates triglyceride and cholesterol levels.
Quelle: Chemical synthesis
Standardisierung: ≥98.0% metformin HCl (HPLC)
Formulare: White crystalline powder
Anwendungen: Pharmaceutical APIs, dietary supplements, research reagents, anti‑aging formulations
| Parameter | Technische Daten |
|---|---|
| Metformin HCl Content (HPLC) | ≥ 98,01 TP3T |
| Identifizierung | IR / UV spectrum conforms to reference |
| pH-Wert (1%-Lösung) | 5.0 – 7.0 |
| Cyanoguanidine (impurity) | ≤ 0.003% |
| Trocknungsverlust | ≤ 0,5% |
| Verbrennungsrückstand | ≤ 0,11 TP3T |
| Schwermetalle (als Pb) | ≤ 10 ppm |
| Arsen (As) | ≤ 1 ppm |
| Grenzwerte für Keime | Entspricht den USP/EP-Standards |
Monatliche Kapazität: über 1.000 kg
Lieferzeit: 3–5 Tage (Proben), 10–15 Tage (Großmengen)
Dokumentation: COA, Sicherheitsdatenblatt
Verpackung: 1 kg, 5 kg, 10 kg, 25 kg
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LyvBio GmbH.
E-Mail: info@lyvbio.com