Sodium Taurocholate Hydrate

Synonyms: Taurocholic acid sodium salt hydrate, Sodium taurocholate, Taurocholic acid sodium salt, Sodium cholate tautaurate, Cholyltaurine sodium salt, Sodium 2-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]aminoethanesulfonate

Sodium Taurocholate Hydrate is the sodium salt of taurocholic acid, a primary bile acid conjugated with taurine, existing as a crystalline hydrate. It is a high-purity bile salt widely used as a biochemical surfactant and solubilizing agent in pharmaceutical and life science research. The product is typically manufactured through chemical synthesis or semi-synthesis from cholic acid, followed by conjugation with taurine and subsequent salt formation, yielding a stable hydrate form.

In the pharmaceutical and biotech industries, Sodium Taurocholate Hydrate serves as a critical excipient for enhancing the solubility and bioavailability of poorly water-soluble drugs, particularly in oral and injectable formulations. It is also a key component in cell culture media, where it facilitates lipid digestion and absorption, and finds use in membrane protein research as a mild detergent for solubilization and reconstitution. Its ability to form mixed micelles makes it indispensable in studies of bile acid metabolism, cholestasis, and drug transport mechanisms.

Product Highlights

• High Purity: ≥98% assay (HPLC) ensures consistent performance in sensitive applications.
• Reliable Supply: Manufactured under cGMP conditions with scalable production capacity to meet bulk demands.
• Regulatory Support: Available with comprehensive documentation including COA, MSDS, and TDS for regulatory submissions.
• Versatile Applications: Suitable for pharmaceutical formulation, cell culture, and biochemical research.
• Custom Packaging: Offered in various pack sizes from grams to kilograms, with custom packaging options.
• Technical Expertise: Backed by a team of experienced chemists providing application-specific support.

Applications

• Solubilizing agent for lipophilic drugs in oral and parenteral formulations.
• Component in cell culture media to enhance lipid uptake and support cell growth.
• Detergent for membrane protein extraction and stabilization in structural biology.
• Reference standard for analytical method development in bile acid research.
• Excipient in drug delivery systems targeting enhanced bioavailability.

Specifications

Ordering & Supply

• Packaging: 1 kg, 5 kg, 25 kg fiber drums with inner polyethylene bags; custom packaging available.
• MOQ: 1 kg (flexible for research quantities).
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS provided with each shipment.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com