Febantel

Từ đồng nghĩa: Febantel, Rintal, Bay 5023, Febantelum, N-[2-[2,3-bis(2-methoxycarbonylamino)benzamido]ethyl]… (full synonyms list)

Febantel is a broad-spectrum anthelmintic belonging to the benzimidazole class, developed for veterinary use. It is a pro-drug that is rapidly metabolized in the body to fenbendazole and oxfendazole, which are the active agents. First introduced in the 1970s, febantel has become a staple in the treatment and control of gastrointestinal nematodes, cestodes, and some trematodes in dogs, cats, and other animals.

Chemically, febantel is a methyl carbamate derivative with a molecular formula of C20H22N4O6S. Its structure features a benzimidazole core with a thioether linkage and a carbamate group, which contributes to its anthelmintic activity. Unlike some benzimidazoles, febantel is not used in human medicine but is widely employed in veterinary formulations, often in combination with praziquantel and pyrantel embonate for comprehensive parasite control.

Commercially, febantel is available as a high-purity powder, typically ≥99.0% assay by HPLC. It is primarily used in the manufacture of oral suspensions, tablets, and pastes for companion animals. Its efficacy against a wide range of parasites, coupled with a favorable safety profile, makes it a preferred choice for deworming protocols in veterinary practice.

Function & Mechanism

• Anthelmintic activity: Febantel acts as a pro-drug, metabolizing to fenbendazole and oxfendazole, which inhibit microtubule polymerization in parasites, leading to energy depletion and death.
• Broad-spectrum efficacy: Effective against nematodes (e.g., Toxocara, Ancylostoma, Trichuris), cestodes (e.g., Taenia), and some trematodes.
• Ovicidal effect: Metabolites also exhibit ovicidal activity, helping to reduce environmental contamination.
• Synergistic combinations: Often combined with praziquantel and pyrantel for expanded coverage.
• Safety profile: Well-tolerated in target species when used as directed.

Nguồn gốc và tiêu chuẩn hóa

• Nguồn: Synthetic chemical, not derived from natural sources.
• Manufacturing: Produced through multi-step organic synthesis, followed by purification and crystallization.
• Tiêu chuẩn hóa: ≥99.0% assay (HPLC), meeting veterinary pharmacopoeia standards.
• Forms: White to off-white crystalline powder.
• Ứng dụng: Veterinary anthelmintic formulations for dogs, cats, and other animals.

Quality Specifications (QC Tests)

Bulk Supply & Documentation

• Công suất hàng tháng: 5 metric tons
• Thời gian thực hiện: 3-5 business days (stock items)
• Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
• Bao bì: 25 kg fiber drum with double polyethylene liner, customized packaging available

Các câu hỏi thường gặp

What is the minimum order quantity (MOQ) for Febantel?

Our standard MOQ is 1 kg. For larger quantities, please contact us for pricing and availability.

How long does delivery take?

For stock items, delivery is typically 3-5 business days from order confirmation. We ship worldwide via express couriers.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, we provide a COA for each batch. Samples are available upon request, typically shipped within 1-2 days.

What are the packaging options?

We offer 25 kg fiber drums with double polyethylene liners as standard. Custom packaging can be arranged to meet specific requirements.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.