Favipiravir

Favipiravir

Tham số Thông số kỹ thuật
Tên sản phẩm Favipiravir
Số CAS 259793-96-9
Công thức phân tử C5H4FN3O2
Trọng lượng phân tử 157.10 g/mol
Hình thức Bột tinh thể màu trắng đến trắng ngà
Phương pháp phân tích (HPLC) ≥99.0%
Độ hòa tan Slightly soluble in water, soluble in DMSO, methanol
Gói 25 kg net weight in fiber drums, double polyethylene bags inside

Favipiravir Structure

Từ đồng nghĩa: Favipiravir, T-705, 6-fluoro-3-hydroxy-2-pyrazinecarboxamide, Avigan, Toyama Chemical

Favipiravir is a broad-spectrum antiviral agent developed by Toyama Chemical (now Fujifilm) in Japan. It is a pyrazinecarboxamide derivative that selectively inhibits the RNA-dependent RNA polymerase (RdRp) of many RNA viruses, including influenza, Ebola, and SARS-CoV-2. Since its approval in Japan in 2014 for pandemic influenza, it has drawn global attention as a potential treatment for emerging viral infections.

Chemically, favipiravir is a synthetic small molecule with a molecular weight of 157.10 g/mol. Its active form, favipiravir-RTP, acts as a purine analog that competes with GTP for incorporation into viral RNA, effectively terminating viral replication. Unlike neuraminidase inhibitors, it targets a broad range of RNA viruses, making it a versatile candidate for antiviral research.

LyvBio supplies high-purity favipiravir (≥99.0% by HPLC) that meets stringent pharmacopeial standards. Our product is manufactured under GMP conditions and is suitable for pharmaceutical manufacturing, clinical research, and antiviral drug development. With reliable supply and comprehensive documentation, we support partners in bringing antiviral therapies to market efficiently.

Function & Mechanism

  • Broad-spectrum antiviral activity: Inhibits replication of influenza A, B, and C viruses, as well as other RNA viruses.
  • RdRp inhibition: Competes with GTP for incorporation into viral RNA, causing chain termination.
  • Activity against emerging viruses: Demonstrates in vitro efficacy against Ebola, Lassa, and SARS-CoV-2.
  • Synergistic potential: May enhance the effects of other antivirals like oseltamivir.
  • Favorable safety profile: Well-tolerated in clinical studies with manageable side effects.

Nguồn gốc và tiêu chuẩn hóa

  • Nguồn: Synthetic chemical synthesis
  • Manufacturing: GMP-compliant process
  • Tiêu chuẩn hóa: ≥99.0% purity by HPLC
  • Forms: White to off-white crystalline powder
  • Ứng dụng: Pharmaceutical manufacturing, clinical research, antiviral drug development

Quality Specifications (QC Tests)

Test Item Thông số kỹ thuật
Xác định IR and HPLC retention time match reference standard
Mất mát khi sấy khô ≤0.5%
Hàm lượng tro sau khi đốt ≤0.1%
Kim loại nặng ≤20 ppm
Giới hạn vi sinh vật Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g
Organic Impurities Any individual impurity ≤0.1%, total impurities ≤0.5%
Chất dung môi còn lại Meets ICH Q3C requirements

Bulk Supply & Documentation

  • Công suất hàng tháng: 500 kg
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
  • Bao bì: 25 kg fiber drums with double polyethylene liners

Các câu hỏi thường gặp

What is the minimum order quantity (MOQ) for Favipiravir?

Our standard MOQ is 1 kg, but we can accommodate smaller quantities for research purposes. Please contact us for specific requirements.

What is the delivery time?

For stock items, delivery is typically 3-5 business days from order confirmation.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, we provide a COA for each batch and can supply samples for evaluation. Sample delivery takes 1-2 days after request.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

send us your specification for a quotation.

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