Dimethylmethoxy Chromanyl Palmitate

Dimethylmethoxy Chromanyl Palmitate

Tên sản phẩm Dimethylmethoxy Chromanyl Palmitate
Số CAS 1105025-85-1
Synonyms Lipochroman-6 palmitate, Dimethylmethoxy chromanol palmitate, 2,2-Dimethyl-6-methoxy-7-(3,5,5-trimethylhexyl)chroman-4-yl palmitate
Hình thức Bột tinh thể màu trắng đến trắng ngà
Công thức phân tử C37H64O4
Trọng lượng phân tử 572.9 g/mol
Phương pháp phân tích (HPLC) ≥98,01 TP3T
Độ hòa tan Soluble in ethanol, isopropyl myristate, and cosmetic esters; practically insoluble in water
Gói 1 kg, 5 kg, 25 kg fiber drums with inner LDPE bags

Dimethylmethoxy Chromanyl Palmitate Structure

Từ đồng nghĩa: Lipochroman-6 palmitate, Dimethylmethoxy chromanol palmitate, 2,2-Dimethyl-6-methoxy-7-(3,5,5-trimethylhexyl)chroman-4-yl palmitate

Dimethylmethoxy Chromanyl Palmitate is a synthetic derivative of dimethylmethoxy chromanol, a potent antioxidant from the chromanol family. While the parent chromanol is renowned for its radical-scavenging activity, its hydrophilic nature limits its compatibility with oil-based formulations. The palmitate ester addresses this by attaching a C16 fatty acid chain to the chromanol core, yielding a lipophilic molecule that integrates seamlessly into emollients, oils, and anhydrous systems. This modification preserves the antioxidant mechanism while enhancing solubility and skin penetration.

At the molecular level, the compound retains the fused benzopyran structure with a methoxy substituent at position 6 and a 3,5,5-trimethylhexyl chain at position 7. The palmitate group at position 4 is ester-linked, masking the phenolic hydroxyl and rendering the molecule more stable against oxidation during storage. Upon topical application, endogenous esterases slowly cleave the ester bond, releasing the active chromanol to exert its antioxidant effects. This pro-drug design ensures sustained release and prolonged activity, making it particularly valuable in anti-aging and protective skincare formulations.

In the personal care industry, Dimethylmethoxy Chromanyl Palmitate is standardized to ≥98% purity by HPLC, a specification that guarantees consistent performance in finished products. It is primarily used as a stabilizer and antioxidant in creams, lotions, and serums, where it helps prevent rancidity of oils and protects skin lipids from oxidative damage. Its oil-soluble nature allows formulators to incorporate it into the oil phase without the need for solubilizers, simplifying production and reducing potential irritation. Typical use levels range from 0.01% to 0.1%, depending on the desired antioxidant protection and product type.

Beyond skincare, this ingredient finds application in color cosmetics and hair care, where oxidative stress can degrade pigments and conditioning agents. Its compatibility with a wide range of cosmetic esters and silicones makes it a versatile additive. As consumer demand for stable, effective antioxidant systems grows, Dimethylmethoxy Chromanyl Palmitate offers a reliable solution backed by solid chemistry and manufacturing consistency.

Chức năng

  • Antioxidant protection: Scavenges free radicals and inhibits lipid peroxidation, safeguarding both formula and skin.
  • Formulation stabilizer: Prevents rancidity of oils and fats, extending product shelf life.
  • Skin conditioning: Supports the skin’s natural antioxidant defenses, reducing signs of oxidative stress.
  • Penetration enhancer: Lipophilic nature aids in delivering the active to deeper skin layers.
  • Anti-aging support: Helps protect collagen and elastin from oxidative degradation.

Nguồn gốc và tiêu chuẩn hóa

  • Nguồn: Synthetic, derived from dimethylmethoxy chromanol and palmitic acid.
  • Production: Esterification of dimethylmethoxy chromanol with palmitoyl chloride, followed by purification.
  • Tiêu chuẩn hóa: ≥98.0% (HPLC).
  • Forms: White to off-white crystalline powder.
  • Ứng dụng: Anti-aging creams, sunscreens, color cosmetics, hair care, anhydrous formulations.

Thông số kỹ thuật

Tham số Thông số kỹ thuật
Phương pháp phân tích (HPLC) ≥98,01 TP3T
Xác định IR and HPLC retention time conform to reference
Hình thức Bột tinh thể màu trắng đến trắng ngà
Mất mát khi sấy khô ≤0.5%
Hàm lượng tro sau khi đốt ≤0.1%
Kim loại nặng ≤10 ppm
Giới hạn vi sinh vật Total aerobic count ≤100 CFU/g; Yeast & Mold ≤10 CFU/g; Absence of E. coli, S. aureus, P. aeruginosa

Documentation & Supply

  • Công suất hàng tháng: 500 kg
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
  • Bao bì: 1 kg, 5 kg, 25 kg fiber drums with inner LDPE bags
  • Lưu trữ: Store in a cool, dry place, away from direct sunlight

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