Aminophenylpyrrole Succinate

Từ đồng nghĩa: Aminophenylpyrrole Succinate, APP Succinate, 3-(4-Aminophenyl)-1H-pyrrole-2,5-dione succinate, Succinate salt of aminophenylpyrrole, Pyrrole-2,5-dione derivative

In the evolving landscape of pharmaceutical intermediates and fine chemicals, few structures bridge the gap between synthetic versatility and biological relevance as elegantly as aminophenylpyrrole derivatives. Aminophenylpyrrole Succinate has quietly become a building block of interest for medicinal chemists and process engineers working on kinase inhibitors, GPCR modulators, and advanced materials. Its appeal lies in the reactive aminophenyl moiety tethered to a pyrrole core, offering a scaffold that can be tailored for diverse applications without compromising on stability or solubility.

At its heart, Aminophenylpyrrole Succinate is the succinic acid salt of a substituted pyrrole, designed to enhance aqueous solubility and handling properties compared to its free base. The succinate counterion not only improves dissolution kinetics but also contributes to a more robust solid-state form, which is often a critical factor in scale-up and formulation. This compound is typically synthesized through a multi-step route starting from commercially available phenylpyrrole precursors, followed by selective amination and salt formation under controlled conditions.

LyvBio supplies Aminophenylpyrrole Succinate with a minimum assay of 98% (HPLC), ensuring consistent purity for demanding research and production environments. Our material is produced under strict quality control protocols, with each batch accompanied by a comprehensive Certificate of Analysis. Whether you are screening new chemical entities or optimizing a synthetic pathway, this intermediate offers a reliable starting point with well-characterized properties.

Product Overview & Composition

Aminophenylpyrrole Succinate is a low-molecular-weight organic salt composed of an aminophenyl-substituted pyrrole core and succinic acid in a 1:1 stoichiometry. The molecular formula C₁₆H₁₉N₃O₄ reflects the presence of one primary amine, one pyrrole nitrogen, and two carboxylic acid groups from the succinate. This composition imparts a balance of lipophilic and hydrophilic character, making it suitable for a range of organic and aqueous-based reactions.

The compound is typically isolated as a crystalline solid, which aids in purification and handling. Its purity profile is tightly controlled, with residual solvents and inorganic impurities kept well below industry thresholds. The succinate salt form also reduces the likelihood of hygroscopicity, a common issue with free bases of similar structure.

Key Applications

• Pharmaceutical Intermediates: Used as a key building block in the synthesis of kinase inhibitors, especially those targeting tyrosine kinases involved in oncology and inflammation.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies, enabling rapid diversification at the aminophenyl and pyrrole positions.
• Material Science: Employed in the development of organic semiconductors and conductive polymers, where the pyrrole core contributes to charge transport properties.
• Agrochemical Synthesis: Acts as a precursor for novel pesticides and herbicides, leveraging the biological activity of aminophenylpyrrole derivatives.
• Bioconjugation: The primary amine group allows for facile conjugation to biomolecules, useful in probe development and targeted drug delivery.

Quality & Standards

Packaging & Supply

• Bao bì: 25 kg net in fiber drum with double polyethylene bags, or customized packaging upon request.
• MOQ: 1 kg for research quantities; 25 kg for commercial orders.
• Thời gian thực hiện: 3-5 business days (stock items)
• Tài liệu hướng dẫn: COA, MSDS, TDS, and stability data available upon request.

Yêu cầu báo giá

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