Pyrrolidine

Pyrrolidine

Tên sản phẩm Pyrrolidine
Số CAS 123-75-1
Các tên gọi khác Tetrahydropyrrole; Azolidine; Prolamine
Công thức phân tử C4H9N
Trọng lượng phân tử 71.12 g/mol
Hình thức Colorless to pale yellow liquid
Assay (GC) ≥99.0%
Moisture (Karl Fischer) ≤0.2%
Gói 170 kg drum

Pyrrolidine Structure

Từ đồng nghĩa: Tetrahydropyrrole, Azolidine, Prolamine, Pyrrole, tetrahydro-

Pyrrolidine is a saturated heterocyclic amine with a five-membered ring, existing as a colorless to pale yellow liquid with a characteristic amine-like odor. It occurs naturally in tobacco leaves and certain animal tissues, but commercial quantities are produced synthetically. As a secondary amine, it serves as a fundamental building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries.

The pyrrolidine ring is a privileged scaffold in drug discovery, appearing in numerous therapeutic agents such as antihypertensives, antipsychotics, and antibiotics. Its basic nitrogen and hydrogen-bonding capability allow it to interact with biological targets, making it a versatile intermediate for constructing complex molecules. Unlike its aromatic counterpart pyrrole, pyrrolidine is fully saturated, which imparts different reactivity and physicochemical properties.

In industrial settings, pyrrolidine is typically manufactured via the hydrogenation of pyrrole or through cyclization reactions of butanediol and ammonia. The product is available in various grades, with high-purity grades (≥99%) preferred for pharmaceutical synthesis. Its applications span from serving as a catalyst in polymerization to a precursor for vulcanization accelerators and agricultural chemicals.

LyvBio supplies pyrrolidine in bulk quantities, ensuring consistent quality and timely delivery to meet the demands of large-scale manufacturing. Our product is backed by comprehensive documentation and technical support, facilitating seamless integration into your production processes.

Chức năng

  • Chất trung gian dược phẩm: Key building block for drugs like procyclidine and captopril.
  • Agrochemical synthesis: Used in the production of fungicides and herbicides.
  • Catalyst: Employed in polymerization reactions and as a curing agent for epoxy resins.
  • Corrosion inhibitor: Protects metals in acidic environments.
  • Solvent: Acts as a polar aprotic solvent in various organic reactions.

Nguồn gốc và tiêu chuẩn hóa

  • Nguồn: Synthetic, derived from petrochemical feedstocks.
  • Manufacturing: Catalytic hydrogenation of pyrrole or cyclization of 1,4-butanediol with ammonia.
  • Tiêu chuẩn hóa: ≥99.0% purity (GC).
  • Forms: Liquid.
  • Ứng dụng: Pharmaceuticals, agrochemicals, rubber chemicals, coatings.

Thông số kỹ thuật

Tham số Thông số kỹ thuật
Assay (GC) ≥99.0%
Xác định IR, NMR conform to structure
Moisture ≤0.2%
Kim loại nặng ≤10 ppm
Color (APHA) ≤50

Documentation & Supply

  • Công suất hàng tháng: 50 metric tons
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
  • Bao bì: 170 kg drum, or customized packaging

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