Pyrrolidine

Synonymes : Tetrahydropyrrole, Azolidine, Prolamine, Pyrrole, tetrahydro-

Pyrrolidine is a saturated heterocyclic amine with a five-membered ring, existing as a colorless to pale yellow liquid with a characteristic amine-like odor. It occurs naturally in tobacco leaves and certain animal tissues, but commercial quantities are produced synthetically. As a secondary amine, it serves as a fundamental building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries.

The pyrrolidine ring is a privileged scaffold in drug discovery, appearing in numerous therapeutic agents such as antihypertensives, antipsychotics, and antibiotics. Its basic nitrogen and hydrogen-bonding capability allow it to interact with biological targets, making it a versatile intermediate for constructing complex molecules. Unlike its aromatic counterpart pyrrole, pyrrolidine is fully saturated, which imparts different reactivity and physicochemical properties.

In industrial settings, pyrrolidine is typically manufactured via the hydrogenation of pyrrole or through cyclization reactions of butanediol and ammonia. The product is available in various grades, with high-purity grades (≥99%) preferred for pharmaceutical synthesis. Its applications span from serving as a catalyst in polymerization to a precursor for vulcanization accelerators and agricultural chemicals.

LyvBio supplies pyrrolidine in bulk quantities, ensuring consistent quality and timely delivery to meet the demands of large-scale manufacturing. Our product is backed by comprehensive documentation and technical support, facilitating seamless integration into your production processes.

Fonction

• Pharmaceutical intermediate: Key building block for drugs like procyclidine and captopril.
• Agrochemical synthesis: Used in the production of fungicides and herbicides.
• Catalyst: Employed in polymerization reactions and as a curing agent for epoxy resins.
• Corrosion inhibitor: Protects metals in acidic environments.
• Solvent: Acts as a polar aprotic solvent in various organic reactions.

Source et normalisation

• Source: Synthetic, derived from petrochemical feedstocks.
• Manufacturing: Catalytic hydrogenation of pyrrole or cyclization of 1,4-butanediol with ammonia.
• Normalisation: ≥99.0% purity (GC).
• Formulaires: Liquid.
• Applications: Pharmaceuticals, agrochemicals, rubber chemicals, coatings.

Caractéristiques techniques

Documentation et approvisionnement

• Capacité mensuelle: 50 metric tons
• Délai de livraison: 3 à 5 jours ouvrés (articles en stock)
• Documentation: Certificat d'analyse (COA), fiche de données de sécurité (FDS) et fiche technique (TDS) disponibles sur demande
• Emballage: 170 kg drum, or customized packaging

Demande de devis

• LyvBio Co. — E-mail : info@lyvbio.com