Ahk-cu

Ahk-cu

Tham số Thông số kỹ thuật
Tên sản phẩm Ahk-cu
Số CAS 49557-75-7
Công thức phân tử C14H22CuN6O4
Trọng lượng phân tử 401.91 g/mol
Hình thức Blue to violet crystalline powder
Phương pháp phân tích (HPLC) ≥98,01 TP3T
Độ hòa tan Soluble in water, slightly soluble in ethanol
Gói 1 kg, 5 kg, 10 kg (double PE bags in fiber drum)

Ahk-cu Structure

Từ đồng nghĩa: Copper tripeptide-3, AHK-Cu, Alanine-Histidine-Lysine copper complex, Copper peptide AHK

Ahk-cu is a synthetic copper-binding tripeptide with the sequence Alanine-Histidine-Lysine. The histidine residue provides a strong imidazole nitrogen donor, allowing the peptide to chelate copper(II) in a stable square-planar geometry. This copper-peptide complex is structurally distinct from the more common GHK-Cu, offering a different spatial arrangement of the amino acid side chains that influences its interaction with cellular targets.

Originally developed for wound healing research, Ahk-cu has gained attention in cosmetic and pharmaceutical formulations for its ability to deliver copper ions to skin and hair follicle cells. The peptide acts as a carrier, facilitating copper uptake and modulating extracellular matrix remodeling. It is typically produced via solid-phase peptide synthesis and supplied as a high-purity powder for topical and research applications.

In the B2B space, Ahk-cu is valued for its stability and compatibility with a range of delivery systems, from serums to creams. Formulators incorporate it into anti-aging and hair care products, where it supports collagen synthesis and antioxidant defense. Its well-defined mechanism and consistent quality make it a reliable active for companies targeting dermatological and regenerative markets.

Cấu trúc và tính chất hóa học

Ahk-cu features a tripeptide backbone with alanine, histidine, and lysine residues. The copper ion is coordinated by the imidazole nitrogen of histidine, the alpha-amino group of alanine, and the amide nitrogen of the peptide bond, forming a stable complex. The lysine side chain remains free, contributing to water solubility and allowing further functionalization if needed. The compound is stable under neutral pH but may dissociate in strongly acidic conditions.

Cơ chế tác dụng

  • Copper delivery: The peptide binds copper(II) and facilitates its transport into cells, where copper acts as a cofactor for enzymes like lysyl oxidase and superoxide dismutase.
  • Collagen stimulation: By delivering copper, Ahk-cu upregulates collagen and elastin synthesis, supporting skin firmness and elasticity.
  • Hệ thống phòng vệ chống oxy hóa: Copper is essential for SOD activity, helping to neutralize free radicals and reduce oxidative stress.
  • Hair follicle support: Studies suggest that Ahk-cu promotes dermal papilla cell proliferation, potentially extending the anagen phase of hair growth.

Quality Specifications (QC Tests)

Test Item Thông số kỹ thuật
Xác định Matches reference standard (HPLC, MS)
Mất mát khi sấy khô ≤5,0%
Hàm lượng tro sau khi đốt ≤0.5%
Kim loại nặng ≤10 ppm
Giới hạn vi sinh vật Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g

Cung ứng và Tài liệu

  • Công suất: 50 kg mỗi tháng
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
  • Bao bì: 1 kg, 5 kg, 10 kg double PE bags in fiber drums

Các câu hỏi thường gặp

What is the MOQ for Ahk-cu?

Our minimum order quantity is 1 kg. For larger quantities, please contact us for pricing and availability.

What is the delivery time?

For stock items, delivery is 3-5 business days after order confirmation.

Do you provide a COA and samples?

Yes, we provide a COA for each batch. Samples are available upon request; sample preparation and dispatch take 1-2 days.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

send us your specification for a quotation.

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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