5-Methoxytryptamine

5-Methoxytryptamine

Product Name 5-Methoxytryptamine
CAS Number 608-07-1
Molecular Formula C₁₁H₁₄N₂O
Molecular Weight 190.24 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) ≥ 98.0%
Melting Point 121–124°C
Heavy Metals ≤ 10 ppm
Storage Cool, dry, sealed, protected from light
Shelf Life 24 months
Package 100g, 500g, 1kg, 5kg, 25kg

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What is 5-Methoxytryptamine?

5-Methoxytryptamine (5-MT) is a naturally occurring tryptamine derivative found in trace amounts in the human body and various plant species. It is structurally characterized by a methoxy group (-OCH₃) at the 5-position of the indole ring.

Structural relationship to other tryptamines:

Compound Structure Key Difference
Tryptamine (CAS 61-54-1) C₁₀H₁₂N₂ Base structure, no substitution
5-Methoxytryptamine (CAS 608-07-1) C₁₁H₁₄N₂O Methoxy group at 5-position
Serotonin (5-HT) (CAS 50-67-9) C₁₀H₁₂N₂O Hydroxy group at 5-position
Melatonin (CAS 73-31-4) C₁₃H₁₆N₂O₂ Methoxy at 5-position + acetylaminoethyl

Key biological role: 5-Methoxytryptamine is a naturally occurring metabolite in the melatonin synthesis pathway. It is formed by the O-methylation of serotonin (5-hydroxytryptamine) via the enzyme hydroxyindole O-methyltransferase (HIOMT).

Important regulatory note: 5-Methoxytryptamine is a research chemical and pharmaceutical intermediate—not a dietary supplement. It is used for legitimate research, analytical standard, and drug synthesis applications. Buyers are responsible for compliance with all applicable laws.

Applications

Application Description End Users
Pharmaceutical intermediate Synthesis of melatonin derivatives and indole-based drugs Pharmaceutical R&D, drug manufacturers
Melatonin pathway research Study of serotonin → melatonin biosynthesis Neuroscience research, chronobiology labs
Receptor binding studies 5-HT receptor (serotonin receptor) pharmacology Pharmacology research, CROs
Analytical reference standard Quantification of 5-MT in biological samples Analytical labs, forensic labs
Organic synthesis Building block for indole-based compound synthesis Chemical R&D

5-Methoxytryptamine vs. Related Compounds

Parameter 5-Methoxytryptamine Serotonin (5-HT) Melatonin Tryptamine
CAS No. 608-07-1 50-67-9 73-31-4 61-54-1
5-position group Methoxy (-OCH₃) Hydroxy (-OH) Methoxy (-OCH₃) None (H)
Side chain Ethylamine Ethylamine Acetylethylamine Ethylamine
Primary use Research, intermediate Research, supplement Supplement, sleep Research, intermediate
Dietary supplement status No Yes (limited) Yes No
Regulatory status Research chemical Supplement (some markets) Supplement (global) Research chemical

LyvBio policy:

  • We sell 5-Methoxytryptamine exclusively for legitimate research and industrial synthesis

  • We reserve the right to refuse sales without documented legitimate purpose

  • Not for human consumption or dietary supplementation

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