Bakuchiol Oil

Bakuchiol Oil

Product Name Bakuchiol Oil
CAS Number 10309-37-2
Molecular Formula C₁₈H₂₄O
Molecular Weight 256.38 g/mol
Appearance Clear to pale yellow viscous oil
Purity ≥ 90% (HPLC), ≥ 98% (High Purity grade)
Density 0.95–1.00 g/cm³
Solubility Soluble in oils, alcohols, glycols; insoluble in water
Storage Cool, dry, sealed, protected from light, under nitrogen (recommended)
Shelf Life 24 months
Package 100g, 500g, 1kg, 5kg, 10kg, 25kg (aluminum bottle or HDPE drum)

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Bakuchiol is a meroterpene phenol naturally found in the seeds and leaves of the Psoralea corylifolia L. plant (also known as Babchi), which has been used in traditional Ayurvedic and Chinese medicine for centuries. Unlike retinol (a synthetic vitamin A derivative), bakuchiol is a plant-derived, non-toxic, non-irritating alternative that delivers comparable anti-aging benefits without the common side effects associated with retinoids.
Bakuchiol is the first natural, non-retinoid compound clinically shown to produce retinol-like effects on collagen synthesis and photoaging without the irritation, redness, peeling, and sun sensitivity associated with retinol.

what-is-bakuchiol

Bakuchiol vs. Retinol: The Scientific Comparison

Parameter Bakuchiol Retinol
Source Natural (plant-derived) Synthetic (vitamin A derivative)
Primary mechanism Retinol-like gene expression (collagen, MMPs) Retinoic acid receptor (RAR/RXR) agonist
Collagen I stimulation  Yes (clinical proof)  Yes
Matrix metalloproteinase (MMP) inhibition Yes Yes
Wrinkle reduction Clinically comparable Gold standard
Skin irritation (erythema, scaling) Minimal (≤ 5%) High (30–60%)
Skin barrier disruption None Significant (TEWL increase)
Photosensitivity / sun sensitivity None Significant (requires sunscreen)
Pregnancy safety Yes (natural, non-retinoid) No (teratogenic risk)
Daytime use Yes (photostable) No (UV-degradable, photosensitizing)
Clean beauty / vegan positioning Excellent Synthetic origin

clinical finding (JCD, 2018): 12-week randomized, double-blind clinical study (n=44) comparing 0.5% bakuchiol twice daily vs. 0.5% retinol once daily showed no significant difference in photoaging improvement (wrinkles, pigmentation, elasticity), but bakuchiol group had significantly less skin scaling and stinging.

Applications

1. Anti-Aging Skincare (Largest Segment)

Application Typical Usage Key Claims
Facial serums 0.5–1.0% Reduces fine lines and wrinkles
Night creams 0.5–1.0% Firms, brightens, renews
Eye creams 0.2–0.5% Reduces crow’s feet, puffiness
Day lotions 0.2–0.5% Protects, smooths, no photosensitivity

2. Retinol Replacement / Retinoid Sensitivity (Fastest Growing Segment)

Application Positioning Target Consumer
Retinol-free anti-aging “Retinol results without the irritation” Sensitive skin, compromised barrier
Pregnancy-safe skincare “Naturally effective” Expecting and nursing mothers
Summer / year-round anti-aging “Daytime-safe” Year-round users (retinol only winter)
Retinol cycling / rotation “Gentle alternative for off nights” Experienced retinol users

3. Acne & Blemish Control

Application Typical Usage Mechanism
Acne serums / spot treatments 0.5–1.0% Anti-inflammatory + antimicrobial
Post-acne marks (PIH) 0.5–1.0% Reduces hyperpigmentation, even tone
Combination acne + anti-aging 0.5–1.0% Treats acne + prevents aging (unique positioning)

4. Body Care

Application Typical Usage Benefits
Chest / décolleté creams 0.2–0.5% Prevents and treats photoaging
Hand creams 0.2–0.5% Smooths, firms, brightens age spots
Body lotions (anti-aging) 0.2–0.5% Full-body renewal, even tone

EXPLORE THE  BAKUCHIOL  OILBENEFITS  AND USES
10O% NATURAL ALTERNATE TO RETINOL

Supplier: LyvBio Co., Ltd.

LyvBio Co., Ltd. is a supplier of high-purity Bakuchiol Oil for the cosmetic and personal care industry.

Supply capabilities:

  • Purity:≥98% (high purity)

  • Natural origin: 100% plant-derived from Psoralea corylifolia seeds

  • Monthly capacity: 1,000+ kg

  • Bulk quantities: 100g – 5,000kg

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

  • Documentation: COA, MSDS, TDS, HPLC chromatogram, stability data, allergen statement, Non-GMO

📧 Inquiries: info@lyvbio.com

FAQs

Q: Is Bakuchiol a retinol?
A: No. Bakuchiol is a plant-derived meroterpene phenol that mimics retinol’s gene expression effects without binding to retinoic acid receptors. It is structurally and mechanistically distinct from vitamin A derivatives.

Q: Is Bakuchiol as effective as retinol?
A: Clinical studies show comparable efficacy for photoaging (wrinkles, pigmentation, elasticity) with significantly fewer side effects. For collagen synthesis and MMP inhibition, bakuchiol performs similarly to retinol.

Q: Can Bakuchiol be used during pregnancy?
A: Yes. Unlike retinol (which is contraindicated due to teratogenic risk), bakuchiol is a natural, non-retinoid compound with no known teratogenic effects. However, consult a physician before use.

Q: Can Bakuchiol be used during the day?
A: Yes. Bakuchiol is photostable and non-photosensitizing, unlike retinol which degrades in UV and increases sun sensitivity. Daytime use is safe and effective, though sunscreen is always recommended.

Q: Can Bakuchiol be combined with retinol?
A: Yes. Bakuchiol can allow lower retinol concentrations (reducing irritation) while maintaining or enhancing efficacy. Some formulators use bakuchiol for “retinol rotation” (retinol one night, bakuchiol the next).

Q: Is Bakuchiol oil-soluble or water-soluble?
A: Bakuchiol is oil-soluble. For water-based serums, it requires solubilizers (polysorbate, PEG-40 hydrogenated castor oil) or emulsification.

Q: How should Bakuchiol be stored?
A: Cool, dry, sealed, protected from light, under nitrogen (recommended for bulk). Shelf life: 24 months.

Q: What is your MOQ?
A: Sample orders: 100g–500g. Trial production: 1–5 kg. Commercial: Negotiable (25kg+ receives volume pricing). Lead time: 3–5 days (samples); 10–15 days (bulk).

Contact LyvBio Co., Ltd.

Ready to formulate with nature’s retinol alternative?

📧 Email: info@lyvbio.com
🌐 Website: https://www.lyvbio.com

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