| Product name | 1-Methylnicotinamide chloride |
| Other name | N-Methylnicotinamide chloride;NMN-Cl;1-MNA chloride;3-carbamoyl-1-methyl-pyridinium chloride |
| CAS No. | 1005-24-9 |
| Molecular formula | C7H9N2OCl |
| Molecular weight | 172.61 |
| Purity | 98.5% |
| Appearance | White – off-white, crystalline solid powder |
| Packing | 1kg/bag;25kg/drum |
| Application | chemical experimental materials |
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1-Methylnicotinamide chloride is a methylated derivative of nicotinamide, characterized by a stable quaternary ammonium salt structure. It serves as a critical intermediate in studying nicotinamide metabolism. Its favorable water solubility and chemical stability render it suitable as a tool compound for biochemical research .
1-MNA is a naturally occurring substance in the human body, functioning as a normal downstream product of niacin metabolism. As an intermediate in this metabolic pathway, 1-MNA is further processed by aldehyde oxidase to generate downstream metabolites such as N-methyl-2-pyridone-5-carboxamide (2PY) and N-methyl-4-pyridone-3-carboxamide (4PY), which are eventually excreted through the urinary system.
Keywords: 1-Methylnicotinamide chloride CAS 1005-24-9, N-Methylnicotinamide chloride, MNA chloride, NNMT research biomarker, niacin metabolite standard, analytical reference standard, LyvBio 1-Methylnicotinamide

3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE
synonym:NICOTINAMIDECHLOROMETHYLATE;
N-METHYLNICOTINICACIDAMIDECHLORIDESALT;
N1-METHYLNICOTINAMIDECHLORIDE;
TRIGONELLAMIDECHLORIDE;
3-(aminocarbonyl)-1-methyl-pyridiniuchloride;
3-carbamoyl-1-methyl-pyridiniuchloride;
nicotinamidemethochloride;
nicotinamidemethylchloride
| Parameter | Specification | Test Method |
|---|---|---|
| Assay (HPLC) | ≥ 98.0% | HPLC |
| Appearance | White to off-white crystalline powder | Visual |
| Identification | HPLC retention time | HPLC |
| Loss on Drying | ≤ 1.0% | USP <731> |
| Residue on Ignition | ≤ 0.1% | USP <281> |
| Heavy Metals | ≤ 10 ppm | ICP-MS |
| Related Substances | Single impurity ≤ 0.5%; Total ≤ 2.0% | HPLC |
Purity: ≥98.0% (HPLC)
Monthly capacity: 10+ kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, TDS, HPLC chromatogram
Packaging: 10g – 1kg
📧 Email: info@lyvbio.com
Q: What is the difference between 1-Methylnicotinamide and Trigonelline?
A: Both are methylated nicotinic acid derivatives. 1-Methylnicotinamide is the methylated form of nicotinamide. Trigonelline is the methylated form of nicotinic acid. They have different CAS numbers and biological roles.
Q: Is 1-Methylnicotinamide chloride water-soluble?
A: Yes. It is freely soluble in water.
Q: What is 1-Methylnicotinamide used as a biomarker for?
A: It is a biomarker for niacin (vitamin B3) status and nicotinamide N-methyltransferase (NNMT) activity in metabolic research.
Q: What is your MOQ?
A: Research samples: 10g–100g. Bulk: 500g–1kg.