Sodium Taurodeoxycholate Hydrate

Sodium taurodeoxycholate hydrate is the sodium salt of taurodeoxycholic acid, a secondary bile acid formed by bacterial 7α-dehydroxylation of taurocholate in the gut. It is supplied as a high-purity (≥98%) crystalline powder, typically containing 3–5% water of hydration, for use in life science research and pharmaceutical formulation development.

This bile salt retains the amphiphilic character essential for micelle formation and lipid solubilization, making it a standard tool in membrane protein extraction, liposome preparation, and intestinal absorption studies. Its low critical micelle concentration relative to trihydroxy bile salts offers distinct advantages in applications requiring milder detergent action.

Synonyms: Taurodeoxycholic acid sodium salt hydrate, Sodium 3α,12α-dihydroxy-5β-cholan-24-oate taurine conjugate, TDCA sodium salt, Sodium taurodeoxycholate, 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonate sodium salt hydrate

Applications

• Membrane protein isolation and stabilization in structural biology
• Lipid nanoparticle and liposome manufacturing for drug delivery
• In vitro models of bile acid physiology and enterohepatic circulation
• Formulation of poorly soluble APIs via micellar solubilization
• Cell culture media supplements for hepatocyte and intestinal models

Quality & Documentation

Each batch is tested for assay (TLC/HPLC ≥98%), loss on drying (≤5.0%), and residual solvents. Comprehensive COA, MSDS, and TDS are provided with every shipment. Stability data under recommended storage conditions (2–8°C, protected from light) are available on request for qualification.

Packaging & Supply

Standard packaging: 100 g, 500 g, 1 kg. Bulk quantities and custom packaging are available. In-stock items ship within 3–5 business days; MOQ is 100 g. For pricing, samples, and bulk orders, contact our sales team.

Request For Quote

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