Phloretin

Phloretin (CAS 60-82-2) is a dihydrochalcone flavonoid predominantly isolated from the root bark of apple trees (Malus spp.) and, to a lesser extent, from pear and other Rosaceae species. It is a natural polyphenol with a unique molecular structure — a chalcone core with two hydroxyl groups — that underlies its well-documented antioxidant, anti-inflammatory, and tyrosinase-inhibitory activities. Our phloretin is supplied as a high-purity crystalline powder (≥98% by HPLC), suitable for cosmetic, nutraceutical, and pharmaceutical research and development.

In formulation, phloretin is valued for its ability to inhibit melanin synthesis and its protective effects against UV-induced oxidative stress, making it a common active ingredient in skin-lightening and anti-aging products. It also shows promise in metabolic health applications, particularly in modulating glucose transport, which has attracted interest from the dietary supplement sector.

Synonyms: Phloretin, 2′,4′,6′-Trihydroxy-3-(4-hydroxyphenyl)propiophenone, Dihydronaringenin, Phloretol, Apple extract derivative

Applications

• Skin care and cosmetic formulations (brightening, anti-aging, UV protection)
• Dietary supplements for metabolic support
• Pharmaceutical research in inflammation and oxidative stress models
• Functional food and beverage development

Quality & Documentation

Each batch is tested for assay (HPLC ≥98%), loss on drying (≤3.0%), and heavy metals (≤10 ppm). Full COA, MSDS, and TDS are provided with every shipment; stability data and residual solvent profiles are available on request for qualification.

Packaging & Supply

Standard packaging: 1 kg, 5 kg, and 25 kg fiber drums with double polyethylene bags inside. Custom packaging can be arranged. In-stock items ship within 3–5 business days; MOQ is 1 kg. For pricing, samples, and bulk orders, contact our sales team.

Request For Quote

• Our Address: 280 Main Street, Xian, Shaanxi, China
• LyvBio Co., Ltd. — Email: info@lyvbio.com