Glucosamine Sulfate

Synonyms: Glucosamine sulfate, D-Glucosamine sulfate, 2-Amino-2-deoxy-D-glucose sulfate, Chitosamine sulfate, Glucosamine sulfuric acid ester

Glucosamine sulfate is the sulfate ester of glucosamine, an amino sugar that occurs naturally in the human body and in the exoskeletons of crustaceans. It is a fundamental building block for glycosaminoglycans, the large molecules that give cartilage its resilience and shock-absorbing properties. In supplement and pharmaceutical applications, it is typically stabilized as a salt—most commonly the potassium or sodium chloride complex—to improve shelf life and bioavailability.

Unlike glucosamine hydrochloride, the sulfate form delivers both glucosamine and sulfate ions, which are directly involved in the synthesis of proteoglycans. This distinction has made it a preferred raw material for joint-health formulations, particularly in Europe where it is often used at higher clinical doses. The sulfate moiety also enhances solubility, facilitating incorporation into liquid and powder blends.

Commercial glucosamine sulfate is produced by hydrolyzing chitin from shellfish shells, followed by sulfation and purification. The resulting material is standardized to a consistent assay, typically ≥99% on a dried basis, and is available in several salt forms to suit different formulation needs. Its well-characterized safety profile and long history of use make it a reliable choice for dietary supplements and pharmaceutical preparations targeting joint and cartilage support.

Function

• Cartilage support: Provides building blocks for glycosaminoglycan synthesis, helping maintain cartilage structure.
• Joint health: Supports joint mobility and comfort by promoting healthy connective tissue.
• Anti-inflammatory activity: May help modulate inflammatory pathways in joint tissues.
• Synovial fluid production: Contributes to the viscosity and lubrication of synovial fluid.

Source & Standardization

• Source: Derived from chitin of crustacean shells (shrimp, crab, lobster).
• Production: Acid hydrolysis of chitin, followed by sulfation and purification.
• Standardization: ≥99% glucosamine sulfate (HPLC), typically stabilized as potassium or sodium chloride complex.
• Forms: White crystalline powder; also available as granulated or micronized grades.
• Applications: Dietary supplements, pharmaceutical tablets/capsules, functional foods, veterinary products.

Specifications

Documentation & Supply

• Monthly capacity: 50 metric tons
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, nutritional analysis, allergen statement
• Packaging: 25 kg fiber drums with double polyethylene liners; custom packaging available

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com