Glucosamine HCl

Synonyms: Glucosamine hydrochloride, 2-Amino-2-deoxy-D-glucose hydrochloride, D-Glucosamine HCl, Chitosamine hydrochloride, 2-Amino-2-deoxy-β-D-glucopyranose hydrochloride

Glucosamine HCl (CAS 66-84-2) is the hydrochloride salt of a naturally occurring amino sugar that plays a fundamental role in the structure of glycosaminoglycans and glycoproteins. While it is found in the shells of crustaceans and the cell walls of fungi, commercial material is almost exclusively produced by acid hydrolysis of chitin, followed by purification and conversion to the stable hydrochloride form. The compound has a well-established history in joint health, but its utility extends well beyond that single application.

In the body, glucosamine serves as a key building block for cartilage matrix components such as aggrecan and hyaluronic acid. The hydrochloride form is preferred over the sulfate salt in many formulations because of its higher solubility in water and its neutral taste, which makes it easier to incorporate into tablets, capsules, and functional beverages. Its molecular formula is C6H13NO5·HCl, with a molecular weight of 215.63 g/mol.

From a manufacturing perspective, Glucosamine HCl is typically standardized to 98–102% on a dried basis, with tight control over chloride content, heavy metals, and microbial limits. The global market for this ingredient remains robust, driven by an aging population and growing interest in preventive orthopedics. It is equally at home in nutraceutical joint formulas, veterinary supplements, and as a research reagent in glycobiology.

Function

• Joint health support: Provides raw material for cartilage glycosaminoglycan synthesis.
• Anti-inflammatory activity: May help modulate inflammatory pathways in joint tissues.
• Hyaluronic acid precursor: Supports the production of synovial fluid components.
• Wound healing: Involved in connective tissue repair and collagen formation.
• Gut health: Emerging research explores its role in intestinal mucosal integrity.

Source & Standardization

• Source: Chitin from shrimp and crab shells (crustacean origin).
• Production: Acid hydrolysis of chitin, followed by hydrochloride salt formation.
• Standardization: ≥ 98% assay (HPLC), low chloride and heavy metal content.
• Forms: White crystalline powder, free-flowing.
• Applications: Dietary supplements, joint health formulations, veterinary products, research.

Specifications

Documentation & Supply

• Monthly capacity: 50 metric tons
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: 25 kg fiber drum with inner polyethylene bag, or as per customer requirements

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com