Modified Citrus Pectin

Modified Citrus Pectin

Product Name Modified Citrus Pectin
CAS Number N/A (polysaccharide complex)
Molecular Weight 10,000 – 30,000 Da (low molecular weight)
Appearance Light beige to off-white fine powder
Assay (Galacturonic Acid, UV-Vis) ≥ 70.0%
Degree of Esterification ≤ 10% (low ester)
Loss on Drying ≤ 8.0%
Residue on Ignition ≤ 6.0%

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Modified Citrus Pectin (MCP) is a low molecular weight, low esterification pectin derived from the peel of citrus fruits (primarily lemons, limes, and oranges) through controlled hydrolysis. Unlike conventional high molecular weight citrus pectin (typically 50,000 – 100,000 Da), MCP is processed to reduce its molecular weight to approximately 10,000 – 30,000 Da, enabling its absorption into the bloodstream and systemic bioavailability.

Modified Citrus Pectin, It is a polysaccharide complex mainly composed of galactose extracted from the skin and flesh of citrus, lemon, orange, grapefruit and other fruits. Its pharmacological effects include anti-tumor, anti-aging, antiviral, anti-inflammatory, anti ulcer, hypoglycemic, lipid-lowering, anticoagulant, and immune function enhancement.

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Modified Citrus Pectin

Standard citrus pectin is a complex polysaccharide rich in galacturonic acid, with a high degree of esterification, making it indigestible and largely confined to the gastrointestinal tract. The modification process reduces the molecular weight and degree of esterification, producing a pectin fragment that is soluble, absorbable, and capable of interacting with cell surface receptors.

MCP has been extensively studied for its ability to bind to galectin‑3, a β‑galactoside‑binding lectin involved in inflammation, fibrosis, and cellular proliferation. By acting as a competitive inhibitor of galectin‑3, MCP supports healthy cellular function, immune modulation, and heavy metal chelation. It has been the subject of clinical investigations in oncology, cardiovascular disease, and inflammatory conditions.

Function

  • Low molecular weight: 10,000 – 30,000 Da, enabling systemic absorption.

  • Galectin‑3 inhibition: Competitively binds to galectin‑3, modulating immune and inflammatory responses.

  • Heavy metal chelation: Supports natural elimination of lead, mercury, and arsenic.

  • Prebiotic activity: Fermented by gut microbiota, supporting gastrointestinal health.

  • Immune modulation: Modulates cytokine production and immune cell activity.

  • Non‑toxic: Well‑tolerated with no significant adverse effects reported.

Source & Modification

  • Source: Citrus fruit peels (lemon, lime, orange, grapefruit)

  • Modification Process: pH adjustment, controlled enzymatic hydrolysis, or heat treatment to reduce molecular weight and esterification

  • Standardization: ≥70.0% galacturonic acid (UV-Vis)

  • Degree of Esterification: ≤10%

  • Forms: Powder (standardized, water‑soluble)

Specifications

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Modified Citrus Pectin-COA

Supply

  • Monthly capacity: 1,000+ kg

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

  • Documentation: COA,TDS, UV‑Vis spectrum, stability data (upon request)

  • Packaging: 1 kg, 5 kg, 10 kg, 25 kg (double‑layer PE bag inside, fiber drum outside)

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