Bromhexine HCl

Bromhexine HCl

Parameter Specification
Product Name Bromhexine HCl
CAS Number 611-75-6
Molecular Formula C14H20Br2N2·HCl
Molecular Weight 412.59 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) 99.0% – 101.0% (on dried basis)
Solubility Slightly soluble in water, soluble in ethanol, practically insoluble in chloroform
Package 25 kg net in fiber drum with double polyethylene liner

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Bromhexine HCl Structure

Synonyms: Bromhexine hydrochloride, N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride, Bromhexine HCl, 611-75-6, Bisolvon, Bromhexine API

Bromhexine HCl is the hydrochloride salt of bromhexine, a synthetic benzylamine-derived mucolytic agent. It appears as a white to off-white crystalline powder, freely soluble in ethanol and slightly soluble in water.

As a pharmaceutical API, it is widely used in oral and injectable formulations for respiratory conditions characterized by thick mucus. It is also a key starting material for the synthesis of ambroxol, its active metabolite.

Product Highlights

  • High Purity: ≥99.0% assay (HPLC), suitable for solid and liquid dosage forms.
  • Reliable Supply: Commercial-scale production with consistent batch-to-batch quality.
  • Regulatory Support: CEP and DMF available for major markets.
  • Documentation: COA, MSDS, TDS provided with every shipment.
  • Flexible Packaging: 25 kg drums, with smaller pack sizes on request.

Applications & Formulation Use

  • Mucolytic and expectorant tablets, syrups, and effervescent granules.
  • Injection solutions for hospital use.
  • Combination products with antibiotics or bronchodilators.
  • Intermediate for ambroxol hydrochloride synthesis.

Quality Specifications (QC Tests)

Test Item Specification
Identification IR spectrum conforms to reference standard
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Organic Impurities Meets EP/USP requirements
Microbial Limits Total aerobic count ≤1000 cfu/g; absence of specified pathogens

Bulk Supply & Ordering

  • Packaging: 25 kg net in fiber drum with double polyethylene liner.
  • MOQ: 25 kg (1 drum).
  • Lead time: 3-5 business days (stock items).
  • Documentation: COA, MSDS, TDS, and regulatory support.

Frequently Asked Questions

What is the MOQ for Bromhexine HCl?

Our standard MOQ is 25 kg (1 drum). For smaller quantities, please contact us to discuss your requirements.

How long does delivery take?

For stock items, lead time is 3-5 business days from order confirmation.

Can you provide a COA and sample?

Yes, a COA is available for each batch. Samples can be provided upon request.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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