5-Deazaflavin

5-Deazaflavin is a synthetic flavin analog where the nitrogen atom at position 5 of the isoalloxazine ring system is replaced by a carbon atom. This seemingly small structural modification significantly alters the redox properties of the molecule, making it a valuable tool for studying flavin-dependent enzymes and electron transfer mechanisms.

Flavins (such as FAD and FMN) are essential coenzymes involved in a wide range of biological redox reactions. Deazaflavin retains the ability to interact with flavin-dependent enzymes but exhibits altered electron transfer characteristics, enabling its use as a mechanistic probe to study flavoprotein function, electron transport, and enzyme catalysis.

Synonyms: Deazaflavin, 5-Deazaflavin, Pyrimido[4,5-b]quinoline-2,4(1H,3H)-dione, NSC 106042, Denitrifying flavin, 1H,2H,3H,4H-Pyrimido[4,5-b]quinoline-2,4-dione, Deazoflavin, Vecabrutinib Impurity 22