Zinc gluconate

Synonyms: Zinc gluconate, Zinc(II) gluconate, Gluconic acid zinc salt, Zinc D-gluconate, Bis(D-gluconato)zinc, Zinc gluconate hydrate

Zinc gluconate is the zinc salt of D-gluconic acid, a polyhydroxy carboxylic acid derived from glucose via fermentation. It appears as a white to off-white crystalline powder that is freely soluble in water, making it a convenient and well-tolerated source of elemental zinc for a wide range of applications. Unlike inorganic zinc salts such as zinc sulfate or zinc oxide, zinc gluconate offers superior gastrointestinal tolerance and higher bioavailability, which has cemented its position as a preferred ingredient in oral zinc supplements and pharmaceutical preparations.

From a chemical standpoint, zinc gluconate consists of a central zinc ion coordinated with two gluconate moieties, forming a stable chelate that readily dissociates in the acidic environment of the stomach to release free zinc ions. This chelation protects the zinc from premature precipitation and enhances its absorption across the intestinal mucosa. The compound delivers approximately 13% elemental zinc by weight, which allows formulators to achieve precise dosing with relatively small amounts of material. Its neutral taste and high water solubility also make it ideal for liquid formulations, effervescent tablets, and syrups where zinc sulfate would be unpalatable or poorly soluble.

Zinc gluconate is widely standardized to a zinc content of 12.0–14.0% on a dried basis, with strict limits on heavy metals, arsenic, and microbial contamination to meet pharmaceutical and nutraceutical grade requirements. It is used extensively in dietary supplements for immune support, cold remedies, skin health, and pediatric nutrition, as well as in cosmetic and personal care products for its soothing and oil-regulating properties. In the pharmaceutical industry, it serves as an active pharmaceutical ingredient (API) in lozenges and topical ointments, while food manufacturers rely on it for fortification of cereals, beverages, and infant formulas.

Function

• Immune support: Zinc is essential for the development and function of immune cells, and supplementation helps reduce the duration and severity of common colds.
• Enzymatic cofactor: Acts as a cofactor for over 300 enzymes involved in metabolism, DNA synthesis, and cell division.
• Wound healing: Supports collagen formation and epithelial tissue repair, making it valuable in dermatological and post-surgical care.
• Antioxidant defense: Contributes to the structure of superoxide dismutase and protects cells from oxidative stress.
• Growth and development: Plays a critical role in physical growth, immune maturation, and neurological development in children.
• Skin health: Helps regulate sebum production and reduce inflammation, commonly used in acne and sensitive skin formulations.

Source & Standardization

• Source: Synthetic chelation of zinc oxide or zinc carbonate with gluconic acid
• Production: Controlled reaction in aqueous medium, followed by crystallization, filtration, and drying
• Standardization: Zinc content 12.0–14.0% (dry basis); complies with USP/EP/BP monographs
• Forms: White to off-white crystalline powder; also available as granules or fine powder upon request
• 응용 분야: Dietary supplements, pharmaceutical lozenges and syrups, food fortification, cosmetic creams, and oral care products

사양

Documentation & Supply

• Monthly capacity: 20 metric tons
• 리드 타임: 3-5 business days (stock items)
• 문서: COA, MSDS, TDS, and regulatory support available upon request
• 포장: 25 kg fiber drums with double polyethylene liners; custom packaging options for small quantities

견적 요청

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