| Product Name | Theobromine |
| CAS Number | 83-67-0 |
| Molecular Formula | C₇H₈N₄O₂ |
| Molecular Weight | 180.16 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥ 99.0% |
| Melting Point | 345–350°C |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Storage | Cool, dry, sealed |
| Shelf Life | 36 months |
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theobromine, The scientific name is 3,7-dimethylxanthine, which has diuretic, myocardial excitatory, vasodilatory, and smooth muscle relaxing effects; It is used as a bitter taste agent in food processing, and is also widely used in biochemical research, drug synthesis, etc.
Chemical classification: Theobromine is a dimethylxanthine, structurally similar to caffeine (trimethylxanthine) and theophylline. It differs from caffeine by having one fewer methyl group.
differentiator: Unlike caffeine, theobromine provides mild, sustained energy without significant central nervous system overstimulation. It has a longer half-life (6–10 hours vs. 3–5 hours for caffeine) and produces less anxiety or jitters.
Synonyms:
3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione
3,7-Dimethylxanthine
Santheose
SC 15090
Diurobromine

| Application | Typical Dosage | Key Claims |
|---|---|---|
| Sustained energy capsules | 100–300 mg | Smooth energy, no crash, no jitters |
| Focus & concentration formulas | 100–200 mg | Mental clarity, sustained attention |
| Caffeine-free energy products | 200–400 mg | Natural alternative to caffeine |
| Application | Typical Dosage | Key Claims |
|---|---|---|
| Pre-workout powders | 100–300 mg | Sustained energy, vasodilation (pumps) |
| Endurance formulas | 200–400 mg | Delayed fatigue, improved blood flow |
LyvBio Co., Ltd. is a GMP-certified supplier of high-purity Theobromine for the nutraceutical, sports nutrition, and functional food industries.
Supply capabilities:
Purity: ≥99.0% (HPLC)
Source: Natural (cacao-derived) or synthetic (food grade)
Monthly capacity: 5,000+ kg
Bulk quantities: 1kg – 20,000kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, TDS, HPLC chromatogram, stability data, allergen statement

| Parameter | Specification | Test Method |
|---|---|---|
| Assay (HPLC) | ≥ 99.0% | HPLC-UV (273 nm) |
| Appearance | White to off-white crystalline powder | Visual |
| Identification | IR, HPLC retention time | USP |
| Melting Point | 345–350°C | USP <741> |
| Loss on Drying | ≤ 0.5% | USP <731> |
| Residue on Ignition | ≤ 0.1% | USP <281> |
| Heavy Metals | ≤ 10 ppm | ICP-MS |
| Related Substances | Single impurity ≤ 0.5%; Total ≤ 1.0% | HPLC-UV |
| Residual Solvents | Meet USP <467> | GC |
| Particle Size | 95% through 80 mesh (customizable) | Sieve Analysis |
Q: Is Theobromine the same as caffeine?
A: No. Theobromine is a different xanthine alkaloid. It has two methyl groups; caffeine has three. Theobromine is 7–10x weaker as a CNS stimulant but provides smoother, longer-lasting energy with fewer side effects.
Q: Is Theobromine safe for daily use?
A: Yes. Theobromine has GRAS status and is well-tolerated at 100–400 mg/day. Long-term use does not build tolerance as quickly as caffeine.
Q: Does Theobromine cause a “crash” like caffeine?
A: No. The longer half-life (6–10 hours) and milder mechanism produce a smoother offset without the afternoon crash associated with caffeine.
Q: Is Theobromine bitter?
A: Yes, but less bitter than caffeine. It can be masked effectively with chocolate, berry, or citrus flavors. Chocolate-flavored products are a natural fit (theobromine is naturally present in cacao).
Q: Can Theobromine be used in caffeine-free products?
A: Yes. This is a primary market positioning. Many consumers want energy without caffeine (jitters, anxiety, sleep disruption). Theobromine is an excellent caffeine alternative.
📧 Email: info@lyvbio.com
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