Theobromine

Theobromine

Product Name Theobromine
CAS Number 83-67-0
Molecular Formula C₇H₈N₄O₂
Molecular Weight 180.16 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥ 99.0%
Melting Point 345–350°C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Storage Cool, dry, sealed
Shelf Life 36 months

Need help? Contact our team

theobromine, The scientific name is 3,7-dimethylxanthine, which has diuretic, myocardial excitatory, vasodilatory, and smooth muscle relaxing effects; It is used as a bitter taste agent in food processing, and is also widely used in biochemical research, drug synthesis, etc.

Chemical classification: Theobromine is a dimethylxanthine, structurally similar to caffeine (trimethylxanthine) and theophylline. It differs from caffeine by having one fewer methyl group.

differentiator: Unlike caffeine, theobromine provides mild, sustained energy without significant central nervous system overstimulation. It has a longer half-life (6–10 hours vs. 3–5 hours for caffeine) and produces less anxiety or jitters.

Synonyms:

  • 3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione

  • 3,7-Dimethylxanthine

  • Santheose

  • SC 15090

  • Diurobromine

Applications & Market Segments

1. Energy & Focus Supplements

Application Typical Dosage Key Claims
Sustained energy capsules 100–300 mg Smooth energy, no crash, no jitters
Focus & concentration formulas 100–200 mg Mental clarity, sustained attention
Caffeine-free energy products 200–400 mg Natural alternative to caffeine

2. Pre-Workout & Sports Nutrition

Application Typical Dosage Key Claims
Pre-workout powders 100–300 mg Sustained energy, vasodilation (pumps)
Endurance formulas 200–400 mg Delayed fatigue, improved blood flow

Supplier: LyvBio Co., Ltd.

LyvBio Co., Ltd. is a GMP-certified supplier of high-purity Theobromine for the nutraceutical, sports nutrition, and functional food industries.

Supply capabilities:

  • Purity: ≥99.0% (HPLC)

  • Source: Natural (cacao-derived) or synthetic (food grade)

  • Monthly capacity: 5,000+ kg

  • Bulk quantities: 1kg – 20,000kg

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

  • Documentation: COA, MSDS, TDS, HPLC chromatogram, stability data, allergen statement

Specifications

Parameter Specification Test Method
Assay (HPLC) ≥ 99.0% HPLC-UV (273 nm)
Appearance White to off-white crystalline powder Visual
Identification IR, HPLC retention time USP
Melting Point 345–350°C USP <741>
Loss on Drying ≤ 0.5% USP <731>
Residue on Ignition ≤ 0.1% USP <281>
Heavy Metals ≤ 10 ppm ICP-MS
Related Substances Single impurity ≤ 0.5%; Total ≤ 1.0% HPLC-UV
Residual Solvents Meet USP <467> GC
Particle Size 95% through 80 mesh (customizable) Sieve Analysis

FAQs

Q: Is Theobromine the same as caffeine?
A: No. Theobromine is a different xanthine alkaloid. It has two methyl groups; caffeine has three. Theobromine is 7–10x weaker as a CNS stimulant but provides smoother, longer-lasting energy with fewer side effects.

Q: Is Theobromine safe for daily use?
A: Yes. Theobromine has GRAS status and is well-tolerated at 100–400 mg/day. Long-term use does not build tolerance as quickly as caffeine.

Q: Does Theobromine cause a “crash” like caffeine?
A: No. The longer half-life (6–10 hours) and milder mechanism produce a smoother offset without the afternoon crash associated with caffeine.

Q: Is Theobromine bitter?
A: Yes, but less bitter than caffeine. It can be masked effectively with chocolate, berry, or citrus flavors. Chocolate-flavored products are a natural fit (theobromine is naturally present in cacao).

Q: Can Theobromine be used in caffeine-free products?
A: Yes. This is a primary market positioning. Many consumers want energy without caffeine (jitters, anxiety, sleep disruption). Theobromine is an excellent caffeine alternative.

📧 Email: info@lyvbio.com
🌐 Website: https://www.lyvbio.com

STAY IN TOUCH

Request For Quote

Our Address

280 Main Street, Xian,Shaanxi,China