Lamotrigine

Lamotrigine

제품명 Lamotrigine
CAS 번호 84057-84-1
분자식 C9H7Cl2N5
분자량 256.09
외관 흰색에서 미백색의 결정성 분말
분석법 (HPLC) 98.0% - 101.0%
건조 손실 ≤ 0.5%
소각 잔류물 ≤ 0.1%
중금속 10 ppm 이하
융점 216°C - 220°C
특정 회전 Not applicable (achiral)

도움이 필요하신가요? 저희 팀에 문의해 주세요

Synonyms :Lamictal, BW-430C, 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine, 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine, Lamotrigine base, Lamotrigine USP

Lamotrigine is a phenyltriazine derivative that functions as an anticonvulsant and mood-stabilizing agent. It is primarily used in the management of epilepsy and bipolar disorder, where it helps to stabilize neuronal membranes by blocking voltage-sensitive sodium channels and inhibiting the release of excitatory neurotransmitters, particularly glutamate. This mechanism of action contributes to its efficacy in reducing seizure frequency and preventing mood episodes.

As a pharmaceutical intermediate, lamotrigine is a key active pharmaceutical ingredient (API) in the production of antiepileptic and psychiatric medications. Its well-characterized profile and established therapeutic benefits make it a valuable compound for both research and commercial applications.

함수

  • Anticonvulsant Activity: Inhibits voltage-gated sodium channels, stabilizing presynaptic neuronal membranes and reducing abnormal electrical discharges in the brain.
  • Glutamate Release Inhibition: Modulates the release of excitatory amino acids, particularly glutamate, thereby dampening excitatory neurotransmission and preventing seizure propagation.
  • Mood Stabilization: Exhibits efficacy in bipolar disorder by prolonging the time to depressive and manic episodes, likely through similar ion channel modulation and neurotransmitter regulation.
  • Neuroprotective Effects: Demonstrates potential neuroprotective properties in models of ischemia and excitotoxicity, supporting its use in neurological conditions.

원산지 및 순도

  • 출처: Synthetic compound produced via chemical synthesis, with high purity suitable for pharmaceutical use.
  • 표준화: Conforms to USP/EP specifications; assay (HPLC) 98.0% – 101.0% on dried basis.
  • 양식: Available as a crystalline powder, typically in bulk quantities for formulation or further processing.
  • 응용 분야: Used as an API in tablets, oral suspensions, and other dosage forms for epilepsy and bipolar disorder; also employed in research and development.

문서 및 공급

  • 문서: COA, MSDS, TDS
  • 리드 타임: 7-15 days after order confirmation, depending on quantity and destination.
  • 포장: Supplied in double polyethylene bags inside fiber drums or as per customer request; net weight 25 kg per drum.

견적 요청

  • 주소: 중국 산시성 시안시 메인 스트리트 280번지
  • LyvBio 주식회사. — 이메일: info@lyvbio.com

How to Order Lamotrigine  from LyvBio? It’s simple!

Just drop us an email at info@lyvbio.com and let us know:

몇 개나 필요하세요?

배송지 주소는 어디인가요?

24시간 이내에 가격, 원산지 증명서(COA) 및 배송 세부 정보를 안내해 드리겠습니다. 샘플 주문과 대량 발송을 모두 지원하며, 유럽 지역에는 DDP(관세 및 세금 포함) 배송이 가능합니다.

연락 유지

견적 요청

주소

280 메인 스트리트, 시안, 산시, 중국

×