| 제품명 | Tauroursodeoxycholic Acid |
|---|---|
| CAS 번호 | 14605-22-2 |
| 분자식 | C₂₆H₄₅NO₆S |
| 분자량 | 499.71 g/mol |
| 외관 | 흰색에서 미백색의 결정성 분말 |
| 분석법 (HPLC) | ≥ 99.0% |
| 용해도 | Soluble in DMSO (up to 30 mg/ml) or
ethanol (up to 20 mg/ml with heating) |
| 건조 손실 | ≤ 0.5% |
| 소각 잔류물 | ≤ 0.1% |
| 중금속 | 10 ppm 이하 |
| 융점 | 173 – 178°C (decompose |
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Tauroursodeoxycholic Acid (TUDCA) is a hydrophilic bile acid, formed by the conjugation of ursodeoxycholic acid (UDCA) with the amino acid taurine. It is a naturally occurring bile acid found in small amounts in human bile and is produced by the liver. TUDCA is the taurine-conjugated form of UDCA and is more hydrophilic than its parent compound, which contributes to its unique biological activities.
TUDCA has attracted considerable scientific interest for its 신경 보호, hepatoprotective, and cytoprotective properties. It functions by inhibiting apoptosis (programmed cell death) through the stabilization of mitochondria and the suppression of the mitochondrial apoptotic pathway. This mechanism is particularly relevant in conditions associated with endoplasmic reticulum stress and mitochondrial dysfunction.
TUDCA is widely used in research on liver health, neuroprotection, and metabolic disorders. It is one of the most extensively studied bile acid derivatives, with a growing body of evidence supporting its potential in treating cholestatic liver diseases, neurodegenerative conditions, and retinal disorders.
Apoptosis inhibition: Stabilizes mitochondria, blocks the mitochondrial apoptotic pathway.
ER stress reduction: Attenuates endoplasmic reticulum stress.
Hepatoprotective effects: Supports liver function in cholestatic conditions.
Neuroprotective activity: Protects neurons from stress-induced apoptosis.
Mitochondrial support: Maintains mitochondrial membrane integrity and function.
항염증 작용: Modulates inflammatory pathways.
출처: Synthetic production (from ursodeoxycholic acid and taurine)
표준화: ≥99.0% TUDCA (HPLC)
양식: White to off-white crystalline powder
응용 분야: Research, dietary supplements, pharmaceutical formulations, neuroprotection studies
| 매개변수 | 사양 |
|---|---|
| TUDCA Content (HPLC) | ≥ 99.0% |
| 식별 | IR / MS / NMR conforms to reference |
| 특정 회전 | +38.0° to +42.0° |
| 융점 | 173 – 178°C (decomposes) |
| 건조 손실 | ≤ 0.5% |
| 소각 잔류물 | ≤ 0.1% |
| 중금속 (Pb 환산) | 10 ppm 이하 |
| 비소 (As) | ≤ 1 ppm |
| 미생물 허용 한도 | USP/EP 기준을 준수합니다 |
| 잔류 용매 | USP 요건을 충족합니다 |
월간 처리 능력: 500+ kg
리드 타임: 3–5 days (samples), 5–7 days (bulk)
문서: COA, MSDS, TDS
포장: 1kg, 5kg, 10kg, 25kg
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이메일: info@lyvbio.com
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