ミノキシジル

ミノキシジル

製品名 ミノキシジル
CAS番号 38304-91-5
分子式 C9H15N5O
分子量 209.25 g/mol
外観 白色からオフホワイトの結晶性粉末
仕様 99.5% (HPLC)
重金属 10 ppm以下
乾燥減量 ≤0.5%
焼失残渣 ≤0.11 TP3T
溶解度 Soluble in water, ethanol, and propylene glycol
パッケージ 25 kg net in fiber drum with double PE liner
仕様 99.5%HPLC

Minoxidil Structure

同義語: 2,4-Diamino-6-piperidinopyrimidine 3-oxide; 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide; U-10858; NSC 757063; Minoxidil

In the personal care and pharmaceutical markets, few active ingredients command as much consistent demand as minoxidil. As a first-line topical agent for androgenetic alopecia, it has become a staple in hair regrowth formulations—from prescription solutions to over-the-counter foams—and continues to drive innovation in men’s grooming and dermatological care. Its well-documented efficacy and favorable safety profile have made it a go-to choice for formulators targeting hair density and scalp health.

Minoxidil is a synthetic piperidinopyrimidine derivative, originally developed as an oral antihypertensive. Its mechanism involves opening potassium channels, which leads to vasodilation and improved microcirculation in hair follicles, thereby prolonging the anagen (growth) phase. Today, it is produced through multi-step chemical synthesis, yielding a highly pure crystalline powder that meets stringent pharmacopeial standards.

LyvBio supplies minoxidil at 99.5% purity (HPLC), a grade suitable for topical pharmaceutical and cosmetic applications. Our material is manufactured under cGMP conditions, with each batch tested for identity, assay, and impurities to ensure consistent performance in finished products.

製品の概要と成分

Minoxidil is a white to off-white crystalline powder with a molecular formula of C9H15N5O and a molecular weight of 209.25 g/mol. It is freely soluble in water, ethanol, and propylene glycol, making it versatile for solution- and foam-based formulations. The compound is stable under normal storage conditions but should be protected from light and moisture to maintain potency.

Our minoxidil is characterized by high purity and low impurity profiles. The synthesis route yields a single active isomer, with no significant related substances. This purity level is critical for topical products, where even trace impurities can affect stability, skin tolerance, or efficacy.

主な用途

  • Hair regrowth solutions: Minoxidil is the active ingredient in topical solutions (2% and 5%) for male and female pattern hair loss.
  • Foam formulations: Used in alcohol-free foams that are easy to apply and suitable for sensitive scalps.
  • Shampoos and conditioners: Added to hair care products for daily use, though stabilizers may be required.
  • Dermatological research: Studied for its effects on hair follicle biology and potential in other alopecia types.
  • Compounding pharmacies: Used in custom topical preparations with other actives like finasteride or tretinoin.

品質と基準

パラメータ 仕様
分析(HPLC) 99.5% min
乾燥減量 ≤0.5%
重金属 10 ppm以下
焼失残渣 ≤0.11 TP3T
Microbial Limits Total aerobic count ≤1000 CFU/g; yeast & mold ≤100 CFU/g; absence of E. coli, Salmonella
粒子径 100% pass through 80 mesh

包装・供給

  • パッケージ: 25 kg net in fiber drum with double polyethylene liner, or as per customer request.
  • 最小注文数量(MOQ): 1 kg for trial orders; 25 kg for standard orders.
  • リードタイム: 3~5営業日(在庫品)
  • ドキュメント: COA, MSDS, TDS, and cGMP certificate available upon request.

見積依頼

  • リブバイオ株式会社. — メールアドレス: info@lyvbio.com

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