Minoxidil

Sinonimi: 2,4-Diamino-6-piperidinopyrimidine 3-oxide; 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide; U-10858; NSC 757063; Minoxidil

In the personal care and pharmaceutical markets, few active ingredients command as much consistent demand as minoxidil. As a first-line topical agent for androgenetic alopecia, it has become a staple in hair regrowth formulations—from prescription solutions to over-the-counter foams—and continues to drive innovation in men’s grooming and dermatological care. Its well-documented efficacy and favorable safety profile have made it a go-to choice for formulators targeting hair density and scalp health.

Minoxidil is a synthetic piperidinopyrimidine derivative, originally developed as an oral antihypertensive. Its mechanism involves opening potassium channels, which leads to vasodilation and improved microcirculation in hair follicles, thereby prolonging the anagen (growth) phase. Today, it is produced through multi-step chemical synthesis, yielding a highly pure crystalline powder that meets stringent pharmacopeial standards.

LyvBio supplies minoxidil at 99.5% purity (HPLC), a grade suitable for topical pharmaceutical and cosmetic applications. Our material is manufactured under cGMP conditions, with each batch tested for identity, assay, and impurities to ensure consistent performance in finished products.

Product Overview & Composition

Minoxidil is a white to off-white crystalline powder with a molecular formula of C9H15N5O and a molecular weight of 209.25 g/mol. It is freely soluble in water, ethanol, and propylene glycol, making it versatile for solution- and foam-based formulations. The compound is stable under normal storage conditions but should be protected from light and moisture to maintain potency.

Our minoxidil is characterized by high purity and low impurity profiles. The synthesis route yields a single active isomer, with no significant related substances. This purity level is critical for topical products, where even trace impurities can affect stability, skin tolerance, or efficacy.

Key Applications

• Hair regrowth solutions: Minoxidil is the active ingredient in topical solutions (2% and 5%) for male and female pattern hair loss.
• Foam formulations: Used in alcohol-free foams that are easy to apply and suitable for sensitive scalps.
• Shampoos and conditioners: Added to hair care products for daily use, though stabilizers may be required.
• Dermatological research: Studied for its effects on hair follicle biology and potential in other alopecia types.
• Compounding pharmacies: Used in custom topical preparations with other actives like finasteride or tretinoin.

Quality & Standards

Packaging & Supply

• Confezionamento: 25 kg net in fiber drum with double polyethylene liner, or as per customer request.
• MOQ: 1 kg for trial orders; 25 kg for standard orders.
• Tempi di consegna: 3-5 business days (stock items)
• Documentazione: COA, MSDS, TDS, and cGMP certificate available upon request.

Richiesta di preventivo

• LyvBio S.r.l. — E-mail: info@lyvbio.com