Celangulin

Celangulin

製品名 Celangulin
CAS番号 116159-73-0
分子式 C₃₀H₄₂O₈ (approximate, for Celangulin I)
分子量 530.65 g/mol (approximate)
外観 Brown to dark brown fine powder
分析(HPLC) ≥ 6.0%
乾燥減量 ≤ 5.0%
焼失残渣 ≤ 8.0%
重金属 10 ppm以下
粒子径 100% ~ 80メッシュ

Celangulin (Celastrus angulatus Extract, 6% Purity)

同義語: Celangulin, Celastrus angulatus Extract, Angled Bittersweet Extract, Celangulin I, Celangulin II, Celangulin III, Insecticidal Sesquiterpenoid, Beta-dihydroagarofuran Sesquiterpenoid

Celangulin is a naturally occurring beta-dihydroagarofuran sesquiterpenoid compound derived from the root bark of Celastrus angulatus (also known as the angled bittersweet or Chinese bittersweet), a climbing shrub native to East Asia. It is one of the principal bioactive components responsible for the plant’s traditional use as a natural insecticide and its more recent applications in agricultural and research settings.

The molecular structure of celangulin features a complex polycyclic sesquiterpenoid skeleton with multiple ester groups, which contribute to its potent insecticidal and antifeedant activities.

The mechanism of action involves disruption of the insect midgut epithelium and interference with the peritrophic membrane, leading to mortality.

Celangulin is available as a 6% standardized extract from Celastrus angulatus root bark. It is primarily used in agricultural research, botanical pesticide development, and as a reference standard for analytical studies.

機能

  • Insecticidal activity: Disrupts insect midgut epithelium and peritrophic membrane.

  • Antifeedant properties: Deters insect feeding through gustatory effects.

  • Botanical pesticide: Active ingredient in natural pest control formulations.

  • 研究ツール: Used in entomological and agricultural research.

  • Analytical standard: Used in HPLC method development and quality control.

出典および標準化

  • 出典: Root bark of Celastrus angulatus

  • 抽出: Hydroalcoholic or solvent extraction, followed by concentration and drying

  • 標準化: ≥6.0% total celangulins (HPLC)

  • フォーム: Brown to dark brown fine powder

よくある質問

Q: What is the mechanism of action of celangulin?
A: Celangulin disrupts the midgut epithelium and peritrophic membrane of insects, leading to digestive dysfunction and mortality. It has both insecticidal and antifeedant activities.

Q: What insects are susceptible to celangulin?
A: Research has shown activity against a range of pests, including lepidopteran larvae, beetles, and aphids.

Q: Is celangulin toxic to mammals?
A: Celastrus angulatus extracts have low mammalian toxicity, making them suitable for botanical pesticide applications. However, pure celangulin should be handled with appropriate laboratory safety precautions.

Q: Is celangulin used in organic farming?
A: Yes, botanical pesticides containing celangulin are permitted in certain organic certification schemes as a natural insecticide.

Q: What is the purity grade available?
A: We supply Celangulin standardized to ≥6.0% total celangulins (HPLC).

 

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