Calcium acetate

Calcium acetate

製品名 Calcium Acetate
CAS番号 62-54-4
別名 Calcium diacetate; Acetic acid calcium salt; Lime acetate; Calcium ethanoate
分子式 C4H6CaO4 (anhydrous); C4H6CaO4·H2O (monohydrate)
分子量 158.17 g/mol (anhydrous); 176.18 g/mol (monohydrate)
外観 White crystalline powder or granules; hygroscopic
アッセイ 99.0%–100.5% (on dried basis, complexometric titration)
乾燥減量 ≤ 7.0% (monohydrate); ≤ 1.0% (anhydrous)
重金属 10 ppm以下
溶解度 Freely soluble in water (approx. 37 g/100 mL at 20°C); slightly soluble in methanol; practically insoluble in ethanol and acetone
pH (5% solution) 6.5 – 8.5
粒子径 Typical 40–100 mesh (customizable)
パッケージ 25 kg net multi-wall paper bags with PE liner; 500 kg / 1000 kg jumbo bags

Calcium acetate Structure

Synonyms: Calcium diacetate, Acetic acid calcium salt, Lime acetate, Calcium ethanoate, Brown acetate

Calcium acetate has become a workhorse in both pharmaceutical and food formulations, driven by two converging trends: the need for effective phosphate binders in an aging CKD population, and the demand for clean-label, shelf-stable calcium fortification in processed foods. Unlike many niche actives, its dual functionality keeps it in steady demand across multiple industries, from renal care to bakery.

Chemically, it is the calcium salt of acetic acid, available in anhydrous and monohydrate forms. The monohydrate is the standard for pharmaceutical use, while the anhydrous grade is often chosen for food and technical applications where moisture control matters. It is produced by reacting acetic acid with calcium carbonate or calcium hydroxide, followed by crystallization and drying.

LyvBio supplies Calcium Acetate in USP/EP/BP grades, with tight control on assay, moisture, and heavy metals. Our material is routinely tested for residual acetic acid and particle size distribution, ensuring consistent performance in direct compression, wet granulation, and blending operations. Whether you are formulating a phosphate binder or a calcium-fortified beverage, our calcium acetate delivers reliable, reproducible results.

製品の概要と成分

Calcium Acetate consists of calcium ions and acetate groups in a 1:2 molar ratio. The monohydrate form contains one molecule of water per formula unit, which influences its solubility and flow properties. The anhydrous form is more hygroscopic and is typically used where low moisture is critical, such as in dry blends or oil-based suspensions.

Both forms are white, odorless powders with a slightly bitter taste. They are freely soluble in water, forming a clear, colorless solution. The pH of a 5% aqueous solution is typically between 6.5 and 8.5, making it compatible with a wide range of excipients and active ingredients.

主な用途

  • Pharmaceutical phosphate binder: Used in patients with chronic kidney disease to reduce serum phosphate levels by binding dietary phosphate in the gastrointestinal tract.
  • Calcium supplement: Provides bioavailable calcium for dietary supplements and functional foods, often combined with vitamin D for enhanced absorption.
  • Food additive: Acts as a firming agent, acidity regulator, and preservative in baked goods, cheeses, and processed vegetables. Also used as a calcium source in beverages.
  • Industrial applications: Employed as a stabilizer in plastics, a mordant in dyeing, and a corrosion inhibitor in water treatment.
  • Laboratory reagent: Used as a source of calcium ions in analytical chemistry and as a buffer component.

品質と基準

パラメータ 仕様
アッセイ 99.0%–100.5%
乾燥減量 ≤ 7.0% (monohydrate)
重金属 10 ppm以下
Arsenic ≤ 3 ppm
Lead ≤ 2 ppm
Microbial Limits Total aerobic count ≤ 1000 CFU/g; Yeast & Mold ≤ 100 CFU/g; E. coli absent

包装・供給

  • パッケージ: 25 kg multi-wall paper bags with PE liner; 500 kg or 1000 kg jumbo bags. Custom packaging available upon request.
  • 最小注文数量(MOQ): 1,000 kg (flexible for trial orders)
  • リードタイム: 3~5営業日(在庫品)
  • ドキュメント: COA, MSDS, TDS, and regulatory support (USP/EP/BP) provided with each shipment.

見積依頼

  • リブバイオ株式会社. — メールアドレス: info@lyvbio.com

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