Semaglutide

Synonyms: Semaglutide, 910463-68-2, GLP-1 receptor agonist, GLP-1 analog, Semaglutide (USAN), Ozempic, Wegovy

Semaglutide is a synthetic analog of the human glucagon-like peptide-1 (GLP-1), a key incretin hormone that regulates glucose metabolism and appetite. It is a 31-amino acid peptide with a fatty acid side chain that enables extended half-life and once-weekly dosing. Developed for the treatment of type 2 diabetes and obesity, semaglutide has become a benchmark in the growing class of GLP-1 receptor agonists.

The molecule was engineered by substituting specific amino acids and attaching a C18 fatty diacid via a hydrophilic spacer, which promotes strong binding to albumin and slows renal clearance. This structural design allows for maintaining therapeutic concentrations over a week, a significant improvement over earlier GLP-1 analogs that required daily injections. Semaglutide is also being investigated for cardiovascular benefits and non-alcoholic steatohepatitis (NASH), reflecting its expanding clinical relevance.

As a research-grade peptide, semaglutide is supplied for laboratory use, including preclinical studies, analytical method development, and formulation research. It is typically offered as a lyophilized powder with a purity of at least 98% by HPLC, ensuring reliable performance in a range of experimental settings.

Funzione

• GLP-1 receptor activation: Stimulates insulin secretion in a glucose-dependent manner.
• Regolazione dell'appetito: Reduces food intake and promotes satiety.
• Beta-cell protection: Supports pancreatic beta-cell function.
• Cardiovascular benefits: May lower risk of major adverse cardiovascular events.

Fonte e standardizzazione

• Fonte: Synthetic peptide, manufactured via solid-phase peptide synthesis.
• Estrazione: Not applicable; produced by chemical synthesis.
• Standardizzazione: Purity ≥98% by HPLC; identity confirmed by mass spectrometry.
• Moduli: Lyophilized powder (as acetate or TFA salt).
• Applicazioni: Research use only; not for human or veterinary use.

Caratteristiche tecniche

Documentazione e forniture

• Capacità mensile: 5 kg
• Tempi di consegna: 5–10 working days after order confirmation
• Documentazione: COA, SDS, TDS
• Imballaggio: Double polyethylene bags inside aluminum foil bag; custom packaging available

Richiesta di preventivo

• Il nostro indirizzo: 280 Main Street, Xian, Shaanxi, Cina
• LyvBio S.r.l. — E-mail: info@lyvbio.com