L-Leucine

L-Leucine

Nom du produit L-Leucine
Numéro CAS 61-90-5
Apparence White crystalline powder or colorless crystals
Caractéristiques techniques USP/EP/AJI
Assay 98.5% – 101.5% (dry basis)
Formule moléculaire C6H13NO2
Poids moléculaire 131.17 g/mol
Solubilité Slightly soluble in water (22.4 g/L at 20°C), practically insoluble in ethanol
Colis 25 kg fiber drum or paper bag with inner PE liner

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L-Leucine Structure

Synonymes : L-Leucine, (S)-2-Amino-4-methylpentanoic acid, L-2-Amino-4-methylpentanoic acid, (S)-Leucine, 2-Amino-4-methylpentanoic acid, L-α-Aminoisocaproic acid

L-Leucine is one of the three branched-chain amino acids (BCAAs) and is widely used in pharmaceutical formulations, clinical nutrition, and sports supplements. Its role in muscle protein synthesis and metabolic regulation has made it a key ingredient in parenteral nutrition solutions and performance products.

As an essential amino acid, L-Leucine cannot be synthesized by the human body and must be obtained from dietary sources. It is commercially produced through microbial fermentation or enzymatic resolution, yielding high-purity material suitable for injectable and oral applications.

Our L-Leucine is available in USP, EP, and AJI grades, with strict control over optical purity and endotoxin levels. It is supplied as a white crystalline powder, free from animal-derived components and suitable for vegetarian and halal formulations.

Présentation et composition du produit

L-Leucine is a non-polar, aliphatic amino acid that plays a critical role in protein synthesis and energy metabolism. It is the most potent of the BCAAs in stimulating muscle protein synthesis, primarily through activation of the mTOR signaling pathway.

In pharmaceutical and nutraceutical applications, L-Leucine is often combined with isoleucine and valine in a 2:1:1 ratio, or used alone in specialized formulas targeting muscle wasting, hepatic encephalopathy, and metabolic support.

Principales applications

  • Pharmaceutical formulations: used in parenteral and enteral nutrition, as well as in oral supplements for muscle wasting and metabolic disorders.
  • Sports nutrition: included in BCAA and pre-workout products to support muscle recovery and endurance.
  • Clinical nutrition: added to amino acid solutions for patients with hepatic impairment or trauma.
  • Food and beverage: used as a flavor enhancer and nutritional fortifier in functional foods.
  • Cell culture media: essential component in biopharmaceutical manufacturing and research.

Qualité et normes

Paramètre Spécifications
Assay (dry basis) 98.5% – 101.5%
Specific Rotation +14.5° to +16.5° (dry basis)
Perte au séchage ≤ 0.2%
Résidu au feu ≤ 0,11 TP3T
Métaux lourds ≤ 10 ppm
Limites microbiologiques Nombre total de bactéries aérobies ≤ 1 000 UFC/g ; levures et moisissures ≤ 100 UFC/g ; absence d'E. coli
Endotoxin ≤ 0.1 EU/mg (for injectable grade)

Emballage et approvisionnement

  • Emballage: 25 kg fiber drums with double polyethylene liners, or 25 kg paper bags for solid dosage applications.
  • Quantité minimale de commande: 25 kg (1 drum)
  • Délai de livraison: 3 à 5 jours ouvrés (articles en stock)
  • Documentation: COA, MSDS, TDS, nutritional analysis, and regulatory support available upon request.

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