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Huperzia serrata extract is a traditional Chinese medicine derived from fir moss, widely used as a cognitive-enhancing dietary supplement due to its active alkaloid, Huperzine A. As a potent acetylcholinesterase (AChE) inhibitor, it is marketed for memory and brain health, with studies suggesting potential, though mixed, benefits for Alzheimer’s disease, dementia, and memory deficits.

Huperzine-A 1% and Huperzine A 99% differ in concentration, sourcing, and applications. Huperzine A 1 is typically derived from the Huperzia serrata plant and blended with carriers, making it suitable for supplements or formulations requiring lower concentrations. In contrast, Huperzine A 99% is a highly pure, concentrated form. Due to the high cost of extracting such purity from natural sources, the mass production of Huperzine A 99% is achieved through chemical synthesis, making it commercially viable. The 1% version caters to consumer-grade products, while the 99% version is ideal for industrial, pharmaceutical, or research applications.

The manufacturing process of Huperzine A 99% powder primarily involves chemical synthesis due to the high cost and limited availability of extracting such purity from natural sources like Huperzia serrata. The process begins with synthesizing intermediate compounds, followed by precise chemical reactions to form the Huperzine A molecule. Advanced purification techniques, such as recrystallization and chromatography, are then employed to achieve 99% purity. This method ensures high yields, cost efficiency, and consistent quality, making it suitable for large-scale production to meet industrial and pharmaceutical demands.
Both ingredients are often used together in nootropic formulas for their complementary effects on acetylcholine pathways.
If you’re looking for Huperzine A powder for your projects and business, or need pricing and bulk purchasing information,
you’ve come to the right place. LyvBio., Ltd. is a professional manufacturer of nutritional ingredients.
We supply Huperzine A powder with a minimum purity of 98%. Any questions about price, COA, MSDS, flow charts, etc.,
we can also deliver DDP to your address in Europe city, include tax, So you dont have to deal with customs
| Item | Specification | Result | Method |
| Appearance | White powder | Complies | Visual |
| Odor | Characteristic | Complies | Organoleptic |
| Taste | Characteristic | Complies | Organoleptic |
| Drying Method | Vacuum drying | Complies | / |
| Loss on Drying | ≤10.0% | 4.30% | TQ-104(105°C/2h) |
| Ash (Sulphated Ash) | ≤10.0% | 5.56% | TQ-104(525°C/3h) |
| Particle Size | NLT 100% Through 80 mesh | Complies | AOAC973.03(TQ_106) |
| Total Heavy Metals | ≤10ppm | Complies | ICP/MS AOAC 993.14 |
| Lead(Pb) | ≤1ppm | Complies | ICP/MS AOAC 993.14 |
| Arsenic(As) | ≤1ppm | Complies | ICP/MS AOAC 993.14 |
| Cadmium (Cd) | ≤1ppm | Complies | ICP/MS AOAC 993.14 |
| Mercury(Hg) | ≤0.05ppm | Complies | ICP/MS AOAC 993.14 |
| Total Plate Count | ≤10,000cfu/g | 5000cfu/g | AOAC996. 23 |
| Total Yeast & Mold | ≤1,000cfu/g | 100cfu/g | (BAM) 7th Ed. |
| E.Coli | Negative | Negative | USP33,NF28,2010 |
| Salmonella | Negative | Negative | USP33,NF28,2010 |
| Staphylococcus | Negative | Negative | USP33,NF28,2010 |
| Conclusion | The product meet the testing requirements | ||