Forskolin
| Paramètre | Spécifications |
|---|---|
| Nom du produit | Forskolin |
| Numéro CAS | 66575-29-9 |
| Formule moléculaire | C22H34O7 |
| Poids moléculaire | 410.5 g/mol |
| Botanical Name | Coleus forskohlii |
| Apparence | Poudre cristalline blanche à blanc cassé |
| Essai (HPLC) | ≥98% |
| Solubilité | Soluble in ethanol, DMSO, methanol; slightly soluble in water |
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Synonymes : Coleus forskohlii extract, Coleonol, Colforsin, 66575-29-9, 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one, Forskolin
Forskolin is a labdane diterpene isolated from the roots of Coleus forskohlii, a plant native to India. It is supplied as a white to off-white crystalline powder, standardized to ≥98% purity by HPLC.
The compound is a cell-permeable activator of adenylyl cyclase, widely used as a research tool in signal transduction studies. Its high purity and well-defined mechanism make it a preferred reference standard for cAMP-related assays.
In the nutraceutical industry, forskolin is formulated into weight management and metabolic support supplements, typically in capsule or tablet form. It is also used in cosmetic formulations for its potential lipolytic properties.
Forskolin is primarily used in two areas: as a biochemical research reagent and as a dietary supplement ingredient. In research, it serves as a positive control or reference standard in assays measuring cAMP levels, often in cell-based experiments. For supplements, it is blended with other ingredients like green tea extract or caffeine in capsules targeting weight management. Cosmetic formulators incorporate it into creams and serums for its purported ability to stimulate lipolysis in adipocytes.
Forskolin is extracted from the dried roots of Coleus forskohlii, which is cultivated in India. The extraction process involves solvent extraction followed by purification steps such as crystallization to achieve high purity. The final product is a fine powder that is stable under recommended storage conditions.
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