Bacopa Monniera Extract

Synonyms: Bacopa monnieri extract, Brahmi extract, Bacopa monniera extract, Bacosides, Herpestis monniera extract

Bacopa Monniera Extract is a standardized botanical concentrate derived from the aerial parts of Bacopa monnieri, a creeping herb native to the wetlands of India, Southeast Asia, and other tropical regions. Known in Ayurveda as Brahmi, this herb has been used for centuries to support memory, cognitive function, and mental clarity. The primary active constituents are bacosides, a group of dammarane-type triterpenoid saponins that are widely studied for their neuroprotective and nootropic properties.

The extract is standardized to contain 20%, 30%, or 50% bacosides (HPLC), ensuring consistent potency and reliability for formulation. It appears as a brown to light brown fine powder with a characteristic herbal aroma. Bacopa Monniera Extract is commonly used in dietary supplements, functional foods, and research studies targeting cognitive health, stress relief, and antioxidant support.

Structure chimique et propriétés

Bacosides are complex saponins featuring a triterpenoid aglycone linked to sugar moieties. The major bacosides, such as bacoside A and bacoside B, share a dammarane skeleton similar to ginsenosides, contributing to their adaptogenic and neuroprotective effects. The compound is amphiphilic, which allows it to interact with lipid membranes and cross the blood-brain barrier, facilitating its action on neuronal signaling pathways.

Mécanisme d'action

• Défense antioxydante: Bacosides scavenge free radicals and reduce oxidative stress in neuronal tissues, protecting against lipid peroxidation.
• Neurotransmitter modulation: They enhance acetylcholine release and choline acetyltransferase activity, improving synaptic transmission and memory.
• Anti-inflammatory activity: Bacosides inhibit pro-inflammatory cytokines (e.g., TNF-α, IL-6) and modulate NF-κB signaling, reducing neuroinflammation.
• Adaptogenic effect: The extract helps the body resist stress by modulating the HPA axis and reducing cortisol levels.
• Synaptic plasticity: It promotes dendritic arborization and hippocampal neurogenesis, supporting long-term cognitive function.

Spécifications de qualité

Approvisionnement et documentation

• Capacité: 5,000 kg per month, with consistent quality across batches.
• Délai de livraison: 7-10 days for standard orders; bulk orders require 2-3 weeks.
• Documentation: COA, allergen statement provided with every shipment.
• Emballage: 25 kg fiber drums with food-grade PE liner, or custom packaging upon request.

Demande de devis

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