| Product Name | 5-Methoxytryptamine |
| CAS Number | 608-07-1 |
| Molecular Formula | C₁₁H₁₄N₂O |
| Molecular Weight | 190.24 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | 121–124°C |
| Heavy Metals | ≤ 10 ppm |
| Storage | Cool, dry, sealed, protected from light |
| Shelf Life | 24 months |
| Package | 100g, 500g, 1kg, 5kg, 25kg |
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5-Methoxytryptamine (5-MT) is a naturally occurring tryptamine derivative found in trace amounts in the human body and various plant species. It is structurally characterized by a methoxy group (-OCH₃) at the 5-position of the indole ring.
Structural relationship to other tryptamines:
| Compound | Structure | Key Difference |
|---|---|---|
| Tryptamine (CAS 61-54-1) | C₁₀H₁₂N₂ | Base structure, no substitution |
| 5-Methoxytryptamine (CAS 608-07-1) | C₁₁H₁₄N₂O | Methoxy group at 5-position |
| Serotonin (5-HT) (CAS 50-67-9) | C₁₀H₁₂N₂O | Hydroxy group at 5-position |
| Melatonin (CAS 73-31-4) | C₁₃H₁₆N₂O₂ | Methoxy at 5-position + acetylaminoethyl |
Key biological role: 5-Methoxytryptamine is a naturally occurring metabolite in the melatonin synthesis pathway. It is formed by the O-methylation of serotonin (5-hydroxytryptamine) via the enzyme hydroxyindole O-methyltransferase (HIOMT).

Important regulatory note: 5-Methoxytryptamine is a research chemical and pharmaceutical intermediate—not a dietary supplement. It is used for legitimate research, analytical standard, and drug synthesis applications. Buyers are responsible for compliance with all applicable laws.
| Application | Description | End Users |
|---|---|---|
| Pharmaceutical intermediate | Synthesis of melatonin derivatives and indole-based drugs | Pharmaceutical R&D, drug manufacturers |
| Melatonin pathway research | Study of serotonin → melatonin biosynthesis | Neuroscience research, chronobiology labs |
| Receptor binding studies | 5-HT receptor (serotonin receptor) pharmacology | Pharmacology research, CROs |
| Analytical reference standard | Quantification of 5-MT in biological samples | Analytical labs, forensic labs |
| Organic synthesis | Building block for indole-based compound synthesis | Chemical R&D |
| Parameter | 5-Methoxytryptamine | Serotonin (5-HT) | Melatonin | Tryptamine |
|---|---|---|---|---|
| CAS No. | 608-07-1 | 50-67-9 | 73-31-4 | 61-54-1 |
| 5-position group | Methoxy (-OCH₃) | Hydroxy (-OH) | Methoxy (-OCH₃) | None (H) |
| Side chain | Ethylamine | Ethylamine | Acetylethylamine | Ethylamine |
| Primary use | Research, intermediate | Research, supplement | Supplement, sleep | Research, intermediate |
| Dietary supplement status | No | Yes (limited) | Yes | No |
| Regulatory status | Research chemical | Supplement (some markets) | Supplement (global) | Research chemical |
LyvBio policy:
We sell 5-Methoxytryptamine exclusively for legitimate research and industrial synthesis
We reserve the right to refuse sales without documented legitimate purpose
Not for human consumption or dietary supplementation
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📧 Email: info@lyvbio.com
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