Huperzia Serrata Extract

Huperzia Serrata Extract

CAS No: 102518-79-6
Botanical source: Dry Huperzta serrata Trev
Test Method: HPLC
Latin Name: Huperzia Serrate P.E
Appearance: Huperzine A 1%, 5% Brown Powder, Huperzine A 98%, 99% White Powder
Specifications: 1% 10% 98%
Molecular Formula: C15H18N2O
Molecular Weight: 242.32
INCI Name: Huperzine A
Applications: Enhancing learning and memory and improving memory impairment
Synonym: (+/-)-HUPERAZINE A;HUPERAZINE A,Huperzia Serrate P.E;Ethanol extracts of Huperzia Serrata;Huperzia Serrate

Need help? Contact our team

What‘s Huperzia Serrata Extract?

Huperzia serrata extract is a traditional Chinese medicine derived from fir moss, widely used as a cognitive-enhancing dietary supplement due to its active alkaloid, Huperzine A. As a potent acetylcholinesterase (AChE) inhibitor, it is marketed for memory and brain health, with studies suggesting potential, though mixed, benefits for Alzheimer’s disease, dementia, and memory deficits.

(±)-Huperzine A is an active alkaloid extracted from traditional Chinese medicine, belonging to the genus Pinus. It is a reversible acetylcholinesterase (ACE) inhibitor and is widely used in Alzheimer’s disease in China.

Information & Health

Action Mechanism: Huperzine A increases levels of acetylcholine, a neurotransmitter critical for memory and learning, by inhibiting the enzyme that breaks it down.

Traditional and Investigated Uses

  1. Cognitive Decline: Used in Asia for treating vascular dementia and Alzheimer’s, showing improvements in cognitive function.
  2. Anti-inflammatory/Neuroprotective: Studies indicate potential neuroprotective effects against glutamate-induced cell death and inflammation.
  3. Alternative Medicine: Traditionally used for fever, inflammation, and blood disorders.

Raw medicinal ingredients

The main active ingredients in the Thousand Layer Pagoda are alkaloids: Huperzine A, Huperzine B, Lycodoline, Lycodavine, Serratini, Huperzine, Serratin, Lycodine, 8-Deoxyserratine, etc. Triterpenes: Serratenediol, 3-acetic acid Serratenediol, 21 epi Serratediol, Serratriol, Tohogenol, etc.

Huperzine a 1% VS Huperzine a 99%

Huperzine-A 1% and Huperzine A 99% differ in concentration, sourcing, and applications. Huperzine A 1 is typically derived from the Huperzia serrata plant and blended with carriers, making it suitable for supplements or formulations requiring lower concentrations. In contrast, Huperzine A 99% is a highly pure, concentrated form. Due to the high cost of extracting such purity from natural sources, the mass production of Huperzine A 99% is achieved through chemical synthesis, making it commercially viable. The 1% version caters to consumer-grade products, while the 99% version is ideal for industrial, pharmaceutical, or research applications.

Huperzine a 99% powder Manufacturing process

The manufacturing process of Huperzine A 99% powder primarily involves chemical synthesis due to the high cost and limited availability of extracting such purity from natural sources like Huperzia serrata. The process begins with synthesizing intermediate compounds, followed by precise chemical reactions to form the Huperzine A molecule. Advanced purification techniques, such as recrystallization and chromatography, are then employed to achieve 99% purity. This method ensures high yields, cost efficiency, and consistent quality, making it suitable for large-scale production to meet industrial and pharmaceutical demands.

Alpha-GPC & Huperzine A: Two Popular Cognitive Enhancers

Alpha-GPC (L-alpha-glycerylphosphorylcholine) is a natural compound found in the brain. It is a precursor to acetylcholine, a neurotransmitter involved in memory and learning. Alpha-GPC is commonly used in supplements to support focus, memory, and overall cognitive function.
Huperzine A is derived from a type of Chinese club moss (Huperzia serrata). It works by inhibiting the enzyme acetylcholinesterase, which breaks down acetylcholine. By slowing down this breakdown, Huperzine A helps maintain higher levels of acetylcholine in the brain — supporting memory and mental clarity.
Both ingredients are often used together in nootropic formulas for their complementary effects on acetylcholine pathways.

Huperzine a Benefits

Huperzine A for Sleep

  • Enhances sleep quality by supporting acetylcholine levels, which regulate the sleep-wake cycle.
  • Improves REM sleep and promotes brain recovery during rest.
  • Reduces mental fatigue for deeper, more restorative sleep.

Huperzine A for ADHD

  • Boosts focus and attention by increasing acetylcholine, essential for learning and memory.
  • Enhances cognitive performance and reduces symptoms of inattention.
  • Supports better task management and mental clarity.

Huperzine A for Bodybuilding (Pre-Workout)

  • Improves neuromuscular communication for better muscle contraction and strength output.
  • Enhances mental focus and endurance through elevated acetylcholine levels.
  • Reduces oxidative stress, promoting faster recovery and sustained performance.

Huperzine A for Anxiety

  • Promotes a calm and focused mind by balancing acetylcholine levels, helping alleviate anxiety symptoms.
  • Enhances cognitive resilience under stress for better emotional regulation.
  • Offers neuroprotective properties to support overall brain health.

Where to buy Huperzine A powder?

If you’re looking for Huperzine A powder for your projects and business, or need pricing and bulk purchasing information,

you’ve come to the right place. LyvBio., Ltd. is a professional manufacturer of nutritional ingredients.

We supply Huperzine A powder with a minimum purity of 98%. Any questions about price, COA, MSDS, flow charts, etc.,

we can also deliver DDP to your address in Europe city, include tax, So you dont have to deal with customs

COA of Huperzia Serrata Extract

Item Specification Result Method
Appearance White powder Complies Visual
Odor Characteristic Complies Organoleptic
Taste Characteristic Complies Organoleptic
Drying Method Vacuum drying Complies /
Loss on Drying ≤10.0% 4.30% TQ-104(105°C/2h)
Ash (Sulphated Ash) ≤10.0% 5.56% TQ-104(525°C/3h)
Particle Size NLT 100% Through 80 mesh Complies AOAC973.03(TQ_106)
Total Heavy Metals ≤10ppm Complies ICP/MS AOAC 993.14
Lead(Pb) ≤1ppm Complies ICP/MS AOAC 993.14
Arsenic(As) ≤1ppm Complies ICP/MS AOAC 993.14
Cadmium (Cd) ≤1ppm Complies ICP/MS AOAC 993.14
Mercury(Hg) ≤0.05ppm Complies ICP/MS AOAC 993.14
Total Plate Count ≤10,000cfu/g 5000cfu/g AOAC996. 23
Total Yeast & Mold ≤1,000cfu/g 100cfu/g (BAM) 7th Ed.
E.Coli Negative Negative USP33,NF28,2010
Salmonella Negative Negative USP33,NF28,2010
Staphylococcus Negative Negative USP33,NF28,2010
Conclusion The product meet the testing requirements

 

STAY IN TOUCH

Request For Quote

Our Address

280 Main Street, Xian,Shaanxi,China