Nicotinato de cobre
| Nombre del producto | Nicotinato de cobre |
|---|---|
| Otros nombres | Nicotinic acid copper salt; Copper(II) nicotinate; Copper pyridine-3-carboxylate |
| Número CAS | 30827-46-4 |
| Fórmula molecular | C12H8CuN2O4 |
| Peso molecular | 307.75 g/mol |
| Apariencia | Blue to blue-green crystalline powder |
| Ensayo (HPLC) | ≥98.0% (on dried basis) |
| Solubilidad | Slightly soluble in water; soluble in dimethyl sulfoxide (DMSO), dimethylformamide (DMF); practically insoluble in ethanol, acetone |
| Pérdida por secado | ≤1.0% |
| Metales pesados | ≤10 ppm |
| Tamaño de las partículas | 98% pass through 80 mesh |
| Paquete | 25 kg net weight in fiber drums with double polyethylene liners |
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Sinónimos: Copper Nicotinate, Nicotinic acid copper salt, Copper(II) nicotinate, Copper pyridine-3-carboxylate, Bis(nicotinato)copper(II), Copper nicotinate complex
Copper Nicotinate is a coordination compound formed between copper(II) ions and nicotinic acid (vitamin B3) ligands, typically in a 1:2 metal-to-ligand ratio. This complex combines the essential trace element copper with the vitamin B3 derivative, offering a dual-action ingredient that has garnered interest in pharmaceutical, nutraceutical, and cosmetic applications. Unlike simple copper salts, the chelated structure of Copper Nicotinate enhances its stability and may improve bioavailability, making it a preferred choice for formulators seeking efficient delivery of both copper and niacin.
Chemically, Copper Nicotinate belongs to the family of metal carboxylate complexes. The nicotinate ligands coordinate to the copper center through the carboxylate oxygen and the pyridine nitrogen, creating a distorted octahedral geometry. This chelation imparts unique electronic properties, including a characteristic blue-green color and paramagnetic behavior. The compound is relatively stable under normal conditions but should be protected from moisture and strong oxidizing agents to prevent decomposition.
In the nutraceutical industry, Copper Nicotinate is used as a source of copper in dietary supplements, often in combination with other minerals. Copper is an essential cofactor for numerous enzymes, including superoxide dismutase and cytochrome c oxidase, and plays a critical role in iron metabolism, connective tissue formation, and antioxidant defense. The nicotinate component may also contribute to vasodilation and lipid metabolism support, although these effects are primarily associated with nicotinic acid at higher doses. In cosmetics, Copper Nicotinate is explored for its potential in skin care formulations targeting wound healing and anti-aging, leveraging copper’s role in collagen synthesis and its antimicrobial properties.
For research and industrial applications, Copper Nicotinate is available in high-purity grades, typically ≥98% as determined by HPLC. It is supplied as a fine crystalline powder, compatible with various formulation processes. Our production adheres to strict quality control measures, ensuring consistent particle size, low heavy metal content, and reliable batch-to-batch uniformity.
| Parámetro | Especificaciones |
|---|---|
| Ensayo (HPLC) | ≥98,01 TP3T |
| Identificación | IR, UV-Vis conforms to structure |
| Pérdida por secado | ≤1.0% |
| Metales pesados | ≤10 ppm |
| Límites microbianos | Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent |
| Tamaño de las partículas | 98% pass 80 mesh |
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